Department of Pharmacognosy, Tohoku Pharmaceutical University, 4-1 Komatsushima 4-chome Aoba-ku, Sendai 981-8558, Japan.
Phytochemistry. 2010 Nov;71(16):1884-91. doi: 10.1016/j.phytochem.2010.08.009.
An 80% acetone extract of Monarda punctata showed an inhibitory effect on lipase activity in isolated mouse plasma in vitro and carvacrol was obtained as the active constituent. It had an IC₅₀ value of 4.07 mM invitro and suppressed elevations in blood triacylglycerol levels in olive oil-loaded mice. Furthermore, from the whole plant, 22 compounds were isolated. Six monoterpene glycosides, a flavone glucuronide, and other known compounds were identified based on the results of spectroscopic analyses.
野芝麻 80%的丙酮提取物对体外分离的小鼠血浆中的脂肪酶活性表现出抑制作用，其中得到的活性成分为香芹酚。它在体外的 IC₅₀ 值为 4.07mM，并抑制橄榄油负荷小鼠的血液三酰甘油水平升高。此外，从整株植物中分离得到 22 种化合物。根据光谱分析的结果，鉴定出 6 种单萜糖苷、一种黄酮葡萄糖醛酸苷和其他已知化合物。
