Human Health Sciences, Graduate School of Medicine, Kyoto University, 53 Shogoin-Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan.
Arch Gerontol Geriatr. 2011 Sep-Oct;53(2):e153-7. doi: 10.1016/j.archger.2010.08.003. Epub 2010 Sep 15.
This study investigated the relationship between age-related declines in muscle thickness of the lower extremities and daily physical activity in elderly women. The subjects comprised 20 young women and 17 elderly women residing in a nursing home. Lower limb muscle thickness was measured by B-mode ultrasound with the following 10 muscles; gluteus maximus, gluteus medius, gluteus minimus, psoas major, rectus femoris, vastus lateralis, vastus intermedius, biceps femoris, gastrocnemius and soleus. Daily physical activity was evaluated using life-space assessment (LSA) which assessed the life-space level, degree of independence, and frequency of attainment. Muscle thickness in the gluteus maximus, gluteus medius, gluteus minimus, psoas major, rectus femoris, vastus lateralis, vastus intermedius, biceps femoris and gastrocnemius, but not soleus, was significantly greater in the young group than the elderly group. The greatest rates of age-related loss of skeletal muscle mass in the lower limbs showed in the psoas major, while the smallest loss showed in soleus muscle. Only the gluteus medius was significantly associated with the LSA score (r = 0.528, p < 0.05) in elderly women. These results suggest that the reduction in skeletal mass with age is smaller in soleus muscle, and that the age-related decline in gluteus medius muscle is influenced by daily physical activity.
本研究调查了下肢肌肉厚度随年龄的下降与老年女性日常体力活动之间的关系。研究对象包括居住在养老院的 20 名年轻女性和 17 名老年女性。通过 B 型超声测量下肢肌肉厚度，共涉及 10 块肌肉，包括臀大肌、臀中肌、臀小肌、腰大肌、股直肌、股外侧肌、股中间肌、股二头肌、腓肠肌和比目鱼肌。使用生活空间评估（LSA）评估日常体力活动，评估内容包括生活空间水平、独立性程度和达成频率。与老年组相比，年轻组的臀大肌、臀中肌、臀小肌、腰大肌、股直肌、股外侧肌、股中间肌、股二头肌和腓肠肌的肌肉厚度显著更大，但比目鱼肌除外。下肢骨骼肌的最大年龄相关性损失率出现在腰大肌中，而最小损失率出现在比目鱼肌中。只有臀中肌与老年女性的 LSA 评分显著相关（r = 0.528，p < 0.05）。这些结果表明，与年龄相关的比目鱼肌骨骼质量减少较小，而臀中肌的年龄相关性下降受日常体力活动的影响。
