Ikezoe Tome, Nakamura Masatoshi, Shima Hiroto, Asakawa Yasuyoshi, Ichihashi Noriaki
Human Health Sciences, Graduate School of Medicine, Kyoto University, 53 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.
Faculty of Health and Sports Sciences, Doshisha University, Kyoto, Japan.
J Physiol Anthropol. 2015 Aug 28;34(1):31. doi: 10.1186/s40101-015-0069-z.
The aim of this study was to investigate the association between walking ability and muscle atrophy in the trunk and lower limbs.
Subjects in this longitudinal study were 21 elderly women who resided in nursing homes. The thicknesses of the following trunk and lower-limb muscles were measured using B-mode ultrasound: rectus abdominis, external oblique, internal oblique, transversus abdominis, erector spinae, lumbar multifidus, psoas major, gluteus maximus, gluteus medius, gluteus minimus, rectus femoris, vastus lateralis, vastus intermedius, biceps femoris, gastrocnemius, soleus, and tibialis anterior. Maximum walking speed was used to represent walking ability. Maximum walking speed and muscle thickness were assessed before and after a 12-month period.
Of the 17 measured muscles of the trunk and lower limbs, age-related muscle atrophy in elderly women was greatest in the erector spinae, rectus femoris, vastus lateralis, vastus intermedius, and tibialis anterior muscles. Correlation coefficient analyses showed that only the rate of thinning of the vastus lateralis was significantly associated with the rate of decline in maximum walking speed (r = 0.518, p < 0.05).
This longitudinal study suggests that reduced walking ability may be associated with muscle atrophy in the trunk and lower limbs, especially in the vastus lateralis muscle, among frail elderly women.
本研究旨在调查躯干和下肢步行能力与肌肉萎缩之间的关联。
这项纵向研究的受试者为21名居住在养老院的老年女性。使用B超测量以下躯干和下肢肌肉的厚度：腹直肌、腹外斜肌、腹内斜肌、腹横肌、竖脊肌、腰多裂肌、腰大肌、臀大肌、臀中肌、臀小肌、股直肌、股外侧肌、股中间肌、股二头肌、腓肠肌、比目鱼肌和胫骨前肌。最大步行速度用于代表步行能力。在12个月期间前后评估最大步行速度和肌肉厚度。
在测量的17块躯干和下肢肌肉中，老年女性与年龄相关的肌肉萎缩在竖脊肌、股直肌、股外侧肌、股中间肌和胫骨前肌中最为明显。相关系数分析表明，只有股外侧肌变薄率与最大步行速度下降率显著相关（r = 0.518，p < 0.05）。
这项纵向研究表明，在体弱的老年女性中，步行能力下降可能与躯干和下肢肌肉萎缩有关，尤其是股外侧肌。
