[褪黑素与松果体切除对大鼠肝脏单加氧酶系统功能的影响]
[The effect of melatonin and epiphysectomy on the function of the mono-oxygenase system in rat liver].
作者信息
Popov A V, Zarubin V V, Arushanian E B, Luneva T M
出版信息
Biull Eksp Biol Med. 1990 Nov;110(11):478-80.
PMID:2083326
Abstract
After chronic melatonin administration (1 mg/kg, 14 days) the content of cytochrome P-450 and activity of NADPH: cytochrome c-reductase in rat microsomes were increased. Pinealectomized rats had opposite directed shifts in microsomal oxidation. In these animals activated effect of melatonin was absent.
摘要
长期给予褪黑素（1毫克/千克，14天）后，大鼠微粒体中细胞色素P-450的含量和NADPH：细胞色素c还原酶的活性增加。松果体切除的大鼠微粒体氧化发生相反方向的变化。在这些动物中，褪黑素的激活作用不存在。
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