Tolpygo S M, Elistratova I A, Pevtsova E I, Komissarova K V, Kotov A V, Gomazkov O A
Biull Eksp Biol Med. 1990 Dec;110(12):563-5.
The results show that during long-term immunization of rats against conjugates of angiotensin II with bovine serum albumin definite age dynamics of immune response have been observed. It was shown that the changes of physiological readings were correlated with growing of antibodies titer against angiotensin II, accordingly, as the immune response was lower, these readings return to the initial level.
结果表明,在大鼠长期免疫血管紧张素II与牛血清白蛋白的结合物过程中,观察到了免疫反应明确的年龄动态变化。结果显示,生理指标的变化与抗血管紧张素II抗体滴度的增加相关,相应地,随着免疫反应降低,这些指标会恢复到初始水平。