Departments of Medicine, Maidstone Hospital, Hermitage Lane, Maidstone, Kent ME16 9QQ, United Kingdom.
Clin Res Hepatol Gastroenterol. 2011 Jan;35(1):55-9. doi: 10.1016/j.gcb.2010.07.016.
Primary peritoneal mesothelioma is a rare and aggressive tumour. We present six consecutive cases treated by our institution in the last three years. All were between 56-65 years old and only one gave a history of direct contact with asbestos. Four of the patients showed a thrombocytosis on presentation but other blood tests and evaluation of ascitic fluid were normal. In all cases, the diagnosis was made through investigation of mixed abdominal symptoms with CT scanning and laparoscopic biopsy. Despite the use of modern chemotherapy, response to treatment was unpredictable, with survival from ten weeks to three years.
原发性腹膜间皮瘤是一种罕见且侵袭性强的肿瘤。我们在此报告过去 3 年来本机构收治的 6 例连续病例。所有患者均为 56-65 岁,只有 1 例有与石棉直接接触的病史。4 例患者就诊时出现血小板增多症,但其他血液检查和腹水评估均正常。所有病例均通过 CT 扫描和腹腔镜活检调查混合性腹部症状进行诊断。尽管采用了现代化疗,但治疗反应不可预测,生存时间从 10 周到 3 年不等。