Sanotskaia N V, Mikhaĭlov V P, Matsievskiĭ D D
Biull Eksp Biol Med. 1990 Dec;110(12):582-6.
In experiments on white rats, guinea pigs and cats it was shown that preliminary infusion of propranolol sharply increases the edemagenous lungs sensitiveness to the infusion of exogenous norepinephrine of white rats and guinea pigs. The infusion of the propranolol to cats leads to a decrease of volume blood flow velocity in the pulmonary artery with the simultaneous difficulty of the outflow in pulmonary veins and to increase of hydrostatic pressure in the lesser circulation. The infusion on that background of epinephrine called the development of temporary sharp hearts failure with the sharp increase of the pressure in pulmonary artery (to 196%) and systemic pressure.
在对白鼠、豚鼠和猫进行的实验中发现，预先注射普萘洛尔会显著增加水肿性肺脏对白鼠和豚鼠外源性去甲肾上腺素注射的敏感性。给猫注射普萘洛尔会导致肺动脉中血流速度降低，同时肺静脉流出受阻，以及小循环中流体静压升高。在此背景下注射肾上腺素会引发暂时性急性心力衰竭，肺动脉压力（升至196%）和体循环压力急剧升高。
