Assunção Renata Almeida de, Liao Adolfo Wenjaw, Brizot Maria de Lourdes, Krebs Vera Lúcia Jornada, Zugaib Marcelo
Clínica Obstétrica, Hospital das Clinicas, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP.
Rev Assoc Med Bras (1992). 2010 Jul-Aug;56(4):447-51. doi: 10.1590/s0104-42302010000400018.
This study aimed to evaluate the perinatal outcome of twin pregnancies delivered in a tertiary teaching hospital according to chorionicity.
A retrospective study involving 289 twin pregnancies delivered from January 2003 to December 2006 was carried out. Maternal and perinatal data were obtained from hospital charts and delivery logs. Chorionicity was determined by ultrasonography or histopathological study.
Incidence of twin gestations was 3.4% and 96.4% were spontaneously conceived. 60.5% were dichorionic (DC), 30.8% of monochorionic diamniotic (MCDA), 6.6% monochorionic monoamniotic (MCMA) and for 2.1% chorionicity was unknown. The mean gestation age at delivery was respectively 35.4, 33.6, 32.9 for DC, MCDA and MCMA. The mean birth weight was 2.171, 1.832 and 1.760 g respectively for DC, MC and MCMA. The proportion of fetuses delivered with less than 34 weeks in DC was of 21.7%, while in MCDA it was of 39.3% and in MCMA of 42.1%. Birth weight below the 10th centile occurred in 15.7% for DC, 22.5% for MCDA and 26.3% in MCMA. Congenital anomalies were observed in 21.3% in monochorionic and in 7.4% in the dichorionic. Length of hospital stay was shorter for DC when compared to MCDA and MCMA twins (13.1, 17.3 and 23.3 days, respectively). The proportion of twin pregnancies with both babies discharged alive were 85.7% in DC and 61.1% in MC.
The rate of preterm deliveries and low birth weight is higher in monochorionic pregnancies when compared to dichorionic twins. However, when adjusted for complications such as fetal abnormalities and twin-twin transfusion syndrome, double survival rates were similar in the two groups.
本研究旨在根据绒毛膜性评估在一家三级教学医院分娩的双胎妊娠的围产期结局。
对2003年1月至2006年12月期间分娩的289例双胎妊娠进行回顾性研究。从医院病历和分娩记录中获取产妇和围产期数据。通过超声检查或组织病理学研究确定绒毛膜性。
双胎妊娠发生率为3.4%,96.4%为自然受孕。60.5%为双绒毛膜(DC),30.8%为单绒毛膜双羊膜囊(MCDA),6.6%为单绒毛膜单羊膜囊(MCMA),2.1%的绒毛膜性未知。DC、MCDA和MCMA的平均分娩孕周分别为35.4、33.6和32.9周。DC、MCDA和MCMA的平均出生体重分别为2.171、1.832和1.760克。DC组孕周小于34周分娩的胎儿比例为21.7%,MCDA组为39.3%,MCMA组为42.1%。DC组出生体重低于第10百分位数的比例为15.7%,MCDA组为22.5%,MCMA组为26.3%。单绒毛膜组先天性畸形的发生率为21.3%,双绒毛膜组为7.4%。与MCDA和MCMA双胎相比,DC双胎的住院时间较短(分别为13.1、17.3和23.3天)。双胎妊娠中两个婴儿均存活出院的比例,DC组为85.7%,MCDA组为61.1%。
与双绒毛膜双胎相比,单绒毛膜双胎的早产率和低出生体重率更高。然而,在调整胎儿异常和双胎输血综合征等并发症后,两组的双胎存活几率相似。