Dipartimento del Farmaco, Istituto Superiore di Sanita, I-00161 Rome, Italy.
Nat Prod Res. 2010 Oct;24(16):1578-86. doi: 10.1080/14786419.2010.500007.
Four new polyketides, (R)-4-hydroxyeleutherin, eleuthone, eleutherinol-8-O-β-D-glucoside and isoeleuthoside C (dihydroisoeleutherin-5-O-β-D-gentiobioside) were isolated from the bulbs of Eleutherine bulbosa, to join eleutherin, isoeleutherin, eleutherinol, eleutherol, eleuthoside B (eleutherol-4-O-β-D-gentiobioside), eleuthoside C (dihydroeleutherin-5-O-β-D-gentiobioside), hongconin (4-oxodihydroisoeleutherin) and elecanacin, which have already been isolated from the same plant. The structures of the new polyketides, based on oxydated cyclic systems, have been elucidated by chemical and spectroscopic methods.
从鳞茎中分离得到 4 种新的多酮类化合物,(R)-4-羟基舞茸醇、舞茸醇、舞茸醇-8-O-β-D-葡萄糖苷和异舞茸醇 C(二氢异舞茸醇-5-O-β-D-龙胆二糖苷),与已从同一植物中分离得到的舞茸醇、异舞茸醇、舞茸醇、舞茸醇、舞茸醇 B(舞茸醇-4-O-β-D-龙胆二糖苷)、舞茸醇 C(二氢异舞茸醇-5-O-β-D-龙胆二糖苷)、hongconin(4-氧代二氢异舞茸醇)和 elecanacin 一起加入其中。这些新的多酮类化合物基于氧化的环状系统,通过化学和光谱方法阐明了它们的结构。