Bergey Meredith R, Steele Matthew S, Bereiter David A, Viali Satupaitea, McGarvey Stephen T
International Health Institute, Brown University, Providence, RI 02912, USA.
Ann Hum Biol. 2011 Mar;38(2):137-45. doi: 10.3109/03014460.2010.499882. Epub 2010 Sep 14.
Ecological and sociodemographic correlates of stress may contribute to cardiovascular disease risk in modernizing Samoans.
The effects of peri-urban vs rural residence, education, occupation, caffeine intake and cigarette consumption on urinary catecholamine excretion were studied in Samoan adults.
Five hundred and seven participants, aged 29-69 years, were randomly selected from nine villages throughout Samoa. Sociodemographic and lifestyle factors were assessed by questionnaire. Epinephrine and norepinephrine excretion rates were measured by high performance liquid chromatography with electrochemical detection in overnight urine samples. Age ( ≤ 40 vs >40 years) and gender-specific regression models were estimated to detect associations with BMI-adjusted catecholamine excretion.
Norepinephrine was significantly higher in peri-urban young men and older women. Epinephrine was significantly higher in peri-urban older men. Adjustment for caffeine attenuated the relationship between residence and norepinephrine in young women.
General residential exposure to modernization in urban villages is a significant correlate of increased overnight catecholamine excretion rates and is consistent with past studies. Caffeine consumption in younger women plays a complex role in stress-related catecholamine excretion. Further studies of individual level attitudinal and behavioural factors in Samoans are needed to understand psychosocial stress, physiologic arousal and health.
压力的生态和社会人口学相关因素可能导致现代化进程中的萨摩亚人患心血管疾病的风险增加。
研究城市周边地区与农村居住环境、教育程度、职业、咖啡因摄入量和吸烟量对萨摩亚成年人尿儿茶酚胺排泄的影响。
从萨摩亚各地的9个村庄中随机选取507名年龄在29至69岁之间的参与者。通过问卷调查评估社会人口学和生活方式因素。采用高效液相色谱-电化学检测法测定过夜尿液样本中的肾上腺素和去甲肾上腺素排泄率。估计年龄（≤40岁与>40岁）和性别特异性回归模型，以检测与体重指数调整后的儿茶酚胺排泄之间的关联。
城市周边地区的年轻男性和老年女性去甲肾上腺素水平显著较高。城市周边地区的老年男性肾上腺素水平显著较高。对咖啡因进行校正后，年轻女性居住环境与去甲肾上腺素之间的关系减弱。
城市村庄普遍受到现代化影响与过夜儿茶酚胺排泄率增加显著相关，这与过去的研究一致。年轻女性摄入咖啡因在与压力相关的儿茶酚胺排泄中起复杂作用。需要对萨摩亚人的个体态度和行为因素进行进一步研究，以了解心理社会压力、生理唤醒和健康状况。
