实验性关节炎和人类类风湿性关节疾病中的蛋白聚糖特异性自身反应性抗体和T淋巴细胞。 - Suppr

Suppr

超能文献

Proteoglycan-specific autoreactive antibodies and T-lymphocytes in experimental arthritis and human rheumatoid joint diseases.

作者信息

Glant T T, Fülöp C, Mikecz K, Buzás E, Molnár G, Erhardt P

机构信息

Department of Biochemistry, Rush-Presbyterian-St. Luke's Medical Center, Chicago, IL 60612.

出版信息

Biochem Soc Trans. 1990 Oct;18(5):796-9. doi: 10.1042/bst0180796.

DOI:10.1042/bst0180796

PMID:2083679

Abstract

摘要

相似文献

Proteoglycan-specific autoreactive antibodies and T-lymphocytes in experimental arthritis and human rheumatoid joint diseases.实验性关节炎和人类类风湿性关节疾病中的蛋白聚糖特异性自身反应性抗体和T淋巴细胞。

Biochem Soc Trans. 1990 Oct;18(5):796-9. doi: 10.1042/bst0180796.

Development of proteoglycan-induced arthritis depends on T cell-supported autoantibody production, but does not involve significant influx of T cells into the joints.蛋白聚糖诱导性关节炎的发展依赖于 T 细胞支持的自身抗体产生，但不涉及 T 细胞大量涌入关节。

Arthritis Res Ther. 2010;12(2):R44. doi: 10.1186/ar2954. Epub 2010 Mar 18.

Immunity to cartilage proteoglycans in BALB/c mice with progressive polyarthritis and ankylosing spondylitis induced by injection of human cartilage proteoglycan.注射人软骨蛋白聚糖诱导的进行性多关节炎和强直性脊柱炎BALB/c小鼠对软骨蛋白聚糖的免疫

Arthritis Rheum. 1987 Mar;30(3):306-18. doi: 10.1002/art.1780300310.

Proteoglycan-induced arthritis in BALB/c mice. Clinical features and histopathology.BALB/c小鼠的蛋白聚糖诱导性关节炎。临床特征与组织病理学

Arthritis Rheum. 1987 Feb;30(2):201-12. doi: 10.1002/art.1780300211.

BALB/c mice genetically susceptible to proteoglycan-induced arthritis and spondylitis show colony-dependent differences in disease penetrance.对蛋白聚糖诱导的关节炎和脊柱炎具有遗传易感性的BALB/c小鼠在疾病发生率上表现出群体依赖性差异。

Arthritis Res Ther. 2009;11(1):R21. doi: 10.1186/ar2613. Epub 2009 Feb 16.

Proteoglycan aggrecan-induced arthritis: a murine autoimmune model of rheumatoid arthritis.蛋白聚糖聚集蛋白聚糖诱导的关节炎：类风湿性关节炎的一种小鼠自身免疫模型。

Methods Mol Med. 2004;102:313-38. doi: 10.1385/1-59259-805-6:313.

Proteoglycan-induced arthritis and recombinant human proteoglycan aggrecan G1 domain-induced arthritis in BALB/c mice resembling two subtypes of rheumatoid arthritis.蛋白聚糖诱导的关节炎以及重组人蛋白聚糖聚集蛋白聚糖G1结构域诱导的BALB/c小鼠关节炎类似于类风湿关节炎的两种亚型。

Arthritis Rheum. 2011 May;63(5):1312-21. doi: 10.1002/art.30261.

Antigen-specific B cells present cartilage proteoglycan (aggrecan) to an autoreactive T cell hybridoma derived from a mouse with proteoglycan-induced arthritis.抗原特异性B细胞将软骨蛋白聚糖（聚集蛋白聚糖）呈递给源自患有蛋白聚糖诱导性关节炎小鼠的自身反应性T细胞杂交瘤。

Clin Exp Immunol. 1995 Sep;101(3):414-21. doi: 10.1111/j.1365-2249.1995.tb03128.x.

Complex pattern of Th1 and Th2 activation with a preferential increase of autoreactive Th1 cells in BALB/c mice with proteoglycan (aggrecan)-induced arthritis.在蛋白聚糖（聚集蛋白聚糖）诱导的关节炎BALB/c小鼠中，Th1和Th2激活模式复杂，自身反应性Th1细胞优先增加。

Clin Exp Immunol. 2000 Apr;120(1):167-73. doi: 10.1046/j.1365-2249.2000.01174.x.

Cell-mediated immunity to collagen and collagen alpha chains in rheumatoid arthritis and other rheumatic diseases.类风湿关节炎及其他风湿性疾病中针对胶原蛋白和胶原蛋白α链的细胞介导免疫。

Am J Med. 1980 Jul;69(1):13-8. doi: 10.1016/0002-9343(80)90494-5.

引用本文的文献

Proteoglycan aggrecan conducting T cell activation and apoptosis in a murine model of rheumatoid arthritis.蛋白聚糖聚集蛋白在类风湿关节炎小鼠模型中诱导 T 细胞激活和凋亡。

Biomed Res Int. 2014;2014:942148. doi: 10.1155/2014/942148. Epub 2014 Jan 29.

Non-MHC risk alleles in rheumatoid arthritis and in the syntenic chromosome regions of corresponding animal models.类风湿关节炎及相应动物模型同线染色体区域中的非主要组织相容性复合体风险等位基因。

Clin Dev Immunol. 2012;2012:284751. doi: 10.1155/2012/284751. Epub 2012 Dec 6.

Aggrecan: A Target Molecule of Autoimmune Reactions.聚集蛋白聚糖：自身免疫反应的靶分子。

Pathol Oncol Res. 1996;2(4):219-228. doi: 10.1007/BF02904814.

Human cartilage aggrecan CS1 region contains cryptic T-cell recognition sites.人软骨聚集蛋白聚糖CS1区域含有隐蔽的T细胞识别位点。

Immunology. 1993 Apr;78(4):586-91.

Effects of leflunomide on immune responses and models of inflammation.来氟米特对免疫反应及炎症模型的影响。

Springer Semin Immunopathol. 1993;14(4):381-94. doi: 10.1007/BF00192310.

Effect of pregnancy on proteoglycan-induced progressive polyarthritis in BALB/c mice: remission of disease activity.妊娠对BALB/c小鼠中蛋白聚糖诱导的进行性多关节炎的影响：疾病活动的缓解

Clin Exp Immunol. 1993 Nov;94(2):252-60. doi: 10.1111/j.1365-2249.1993.tb03440.x.

Clin Exp Immunol. 1995 Sep;101(3):414-21. doi: 10.1111/j.1365-2249.1995.tb03128.x.

Human cartilage proteoglycans as T cell autoantigens.人软骨蛋白聚糖作为T细胞自身抗原。

Ann Rheum Dis. 1992 Sep;51(9):1094-7. doi: 10.1136/ard.51.9.1094.

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