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抗 NMDA 受体脑炎伴 MRI 不典型脑改变。

Anti-NMDA receptor encephalitis with atypical brain changes on MRI.

机构信息

Division of Child Neurology/Developmental Paediatrics/Neurohabilitation, Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China.

出版信息

Pediatr Neurol. 2010 Oct;43(4):274-8. doi: 10.1016/j.pediatrneurol.2010.05.004.

Abstract

A young girl with antibodies to the N-methyl-D-aspartate receptor presented with a clinical syndrome suggestive of dyskinetic encephalitis lethargica with neuropsychiatric features at presentation, movement disorder, mutism, sleep disorder, and seizures. Persistent lesions in the white matter and pons were observed in magnetic resonance imaging of the brain, findings that have not been described previously in N-methyl-D-aspartate receptor antibody encephalitis.

摘要

一位年轻女孩体内存在抗 N-甲基-D-天冬氨酸受体抗体,其临床表现为伴有神经精神特征的发作性睡病伴多动性脑病,存在运动障碍、缄默症、睡眠障碍和癫痫。脑部磁共振成像显示,大脑的白质和脑桥存在持续性病变,这在以前的 N-甲基-D-天冬氨酸受体抗体脑炎中并未描述过。

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