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手术量-结局关系与腹主动脉瘤修复。

Volume-outcome relationships and abdominal aortic aneurysm repair.

机构信息

Department of Health Care Policy, Harvard Medical School, 180 Longwood Ave, Boston, MA 02215, USA.

出版信息

Circulation. 2010 Sep 28;122(13):1290-7. doi: 10.1161/CIRCULATIONAHA.110.949172. Epub 2010 Sep 13.

Abstract

BACKGROUND

There is a well-established literature relating procedure volume to outcomes, but incorporating such information into clinical decision making is problematic when there is >1 treatment option for a condition.

METHODS AND RESULTS

We used data from the Medicare program to investigate the relationship between institutional volume for open and endovascular abdominal aortic aneurysm (AAA) repair and outcomes, examine trends in volume, and explore the implications for physicians making referrals for AAA repair. Trends in institutional volume were measured for the time period 2001-2006, whereas outcomes were assessed with the use of a previously assembled propensity score-matched cohort covering the time period 2001-2004. Between 2001 and 2006, there were a total of 230 736 repairs of either an intact or ruptured AAA for traditional Medicare beneficiaries. During this time, the proportion of endovascular cases increased from ≈22 in 2001 to >50 of AAA repairs in 2006, but there was little shift in procedure volume to high-volume institutions. For endovascular repair, adjusted mortality by quintile showed a marked decrease between the first and second quintile, with continued smaller decreases over quintiles 3 to 5. For open repair, adjusted mortality showed a steady decrease across the quintiles of volume.

CONCLUSIONS

We found a steady increase in survival with increasing volume of open repair but relatively little improvement after reaching a relatively low threshold for endovascular repair. Because hospital experience with one repair method does not translate into improved outcomes for the alternative method, referring clinicians must consider both treatment options when making referral decisions.

摘要

背景

有大量文献证实手术量与治疗效果之间存在关联,但当一种疾病存在多种治疗选择时,将此类信息纳入临床决策就会变得很复杂。

方法和结果

我们利用医疗保险计划的数据,研究了开放性和血管内腹主动脉瘤(AAA)修复的机构手术量与治疗效果之间的关系,考察了手术量的变化趋势,并探讨了对为 AAA 修复提供转诊的医生的影响。在 2001-2006 年期间测量了机构手术量的变化趋势,而治疗效果则使用之前组建的倾向评分匹配队列进行评估,涵盖 2001-2004 年期间。在 2001 年至 2006 年期间,共有 230736 例传统 Medicare 受益人的完整或破裂性 AAA 进行了修复。在此期间,血管内病例的比例从 2001 年的 ≈22%增加到 2006 年的 AAA 修复的>50%,但高容量机构的手术量几乎没有转移。对于血管内修复,按五分位数调整的死亡率显示,在第一和第二五分位数之间有明显下降,在第三至五分位数之间持续下降。对于开放性修复,调整后的死亡率在五分位数的体积范围内呈稳步下降。

结论

我们发现开放性修复的手术量增加与生存率的提高呈正相关,但在达到血管内修复的相对较低阈值后,改善相对较小。由于医院在一种修复方法方面的经验并不能转化为另一种方法的治疗效果的改善,因此在做出转诊决策时,转介临床医生必须同时考虑两种治疗选择。

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