Flammer J
Universitäts-Augenklinik, Basel.
Fortschr Ophthalmol. 1990;87 Suppl:S187-9.
Normal tension glaucoma is defined as a clinical condition in which the optic nerve head is pathologically excavated and the visual field is disturbed, although the intraocular pressure is in the normal range. The following pathogenetic factors are considered responsible: too high IOP (even lying within the normal range) and primary circulatory disturbances, such as arteriosclerosis, systemic hypotension, orthostatic hypotension, hyperviscosity and functional vasospasms. The purpose of a clinical evaluation is to define the most important damaging factors for the individual patient. Accordingly, the therapy is directed towards the possible factors involved. Practically, this can mean: additional lowering of the intraocular pressure, increasing the blood pressure, lowering the blood viscosity and treating the vasospasms.
正常眼压性青光眼被定义为一种临床病症,即尽管眼压在正常范围内,但视神经乳头发生病理性凹陷且视野受到干扰。以下致病因素被认为与此有关:眼压过高(即使在正常范围内)以及原发性循环障碍,如动脉硬化、全身性低血压、体位性低血压、血液高黏滞度和功能性血管痉挛。临床评估的目的是确定个体患者最重要的损伤因素。因此,治疗针对可能涉及的因素。实际上,这可能意味着:进一步降低眼压、升高血压、降低血液黏滞度以及治疗血管痉挛。