Findlay J K, Liew S H, Simpson E R, Korach K S
Prince Henry's Institute of Medical Research, 5152, Clayton, VIC, 3168, Australia.
Handb Exp Pharmacol. 2010(198):29-35. doi: 10.1007/978-3-642-02062-9_2.
Estrogens influence fertility and infertility in animals. This chapter reviews the use of estrogen as a contraceptive through the regulation of its production and action. It is concluded that the use of specific agonists and antagonists of estrogen action that avoid the global and unwanted side effects of estrogen offers new potential methods of contraception.
雌激素影响动物的生育能力和不孕情况。本章综述了通过调节雌激素的产生和作用将其用作避孕药的情况。得出的结论是,使用能避免雌激素全身性不良副作用的雌激素作用特异性激动剂和拮抗剂提供了新的潜在避孕方法。