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Diagnosing an ulcerated gouty tophus.诊断溃疡性痛风石。
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本文引用的文献

1
New insights into the epidemiology of gout.痛风流行病学的新见解。
Rheumatology (Oxford). 2009 May;48 Suppl 2:ii2-ii8. doi: 10.1093/rheumatology/kep086.
2
Receptor-independent, direct membrane binding leads to cell-surface lipid sorting and Syk kinase activation in dendritic cells.不依赖受体的直接膜结合导致树突状细胞中的细胞表面脂质分选和Syk激酶激活。
Immunity. 2008 Nov 14;29(5):807-18. doi: 10.1016/j.immuni.2008.09.013.
3
SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout.溶质载体家族2成员9(SLC2A9)是一种新发现的尿酸转运蛋白,可影响血清尿酸浓度、尿酸排泄及痛风。
Nat Genet. 2008 Apr;40(4):437-42. doi: 10.1038/ng.106. Epub 2008 Mar 9.
4
Gout in the UK and Germany: prevalence, comorbidities and management in general practice 2000-2005.英国和德国的痛风:2000 - 2005年全科医疗中的患病率、合并症及管理
Ann Rheum Dis. 2008 Jul;67(7):960-6. doi: 10.1136/ard.2007.076232. Epub 2007 Nov 2.
5
Elderly-onset gout: a review.老年痛风:综述
Rheumatol Int. 2007 Nov;28(1):1-6. doi: 10.1007/s00296-007-0421-7. Epub 2007 Jul 26.
6
Uric acid nephrolithiasis.尿酸肾结石
Curr Rheumatol Rep. 2007 Jun;9(3):251-7. doi: 10.1007/s11926-007-0040-z.
7
Cardiff Wound Impact Schedule: the development of a condition-specific questionnaire to assess health-related quality of life in patients with chronic wounds of the lower limb.加的夫伤口影响量表:开发一种针对特定病情的问卷,以评估下肢慢性伤口患者与健康相关的生活质量。
Int Wound J. 2004 Apr;1(1):10-7. doi: 10.1111/j.1742-481x.2004.00007.x.
8
Gout-associated uric acid crystals activate the NALP3 inflammasome.痛风相关的尿酸晶体激活NALP3炎性小体。
Nature. 2006 Mar 9;440(7081):237-41. doi: 10.1038/nature04516. Epub 2006 Jan 11.
9
The prevalence of metabolic syndrome in patients with gout: a multicenter study.痛风患者中代谢综合征的患病率:一项多中心研究。
J Korean Med Sci. 2005 Dec;20(6):1029-33. doi: 10.3346/jkms.2005.20.6.1029.
10
Tophaceous gout: quantitative evaluation by direct physical measurement.痛风石性痛风:通过直接体格测量进行定量评估。
J Rheumatol. 2005 Dec;32(12):2368-72.

溃疡性痛风石

Ulcerated tophaceous gout.

机构信息

Department of Dermatology and Wound Healing, School of Medicine, Cardiff University, Heath Park, Cardiff CF14 4XN, UK.

出版信息

Int Wound J. 2010 Oct;7(5):423-7. doi: 10.1111/j.1742-481X.2010.00700.x.

DOI:10.1111/j.1742-481X.2010.00700.x
PMID:20840184
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7951191/
Abstract

Gout is often considered a disease of an excessive lifestyle, a 'malady of kings'. Today, more than 1% of the European and US populations are afflicted with gout, although ulceration over gout tophi remains uncommon. We describe four cases of ulceration associated with gout tophi to highlight the clinical presentation, complications and a management strategy.

摘要

痛风通常被认为是一种过度生活方式引起的疾病,是一种“帝王病”。如今,超过 1%的欧洲和美国人口患有痛风,尽管痛风石溃疡仍然少见。我们描述了四例与痛风石相关的溃疡病例,以突出其临床表现、并发症和治疗策略。