新加坡帕金森病的经济负担。

Economic burden of Parkinson's disease in Singapore.

机构信息

Department of Pharmacy, National University of Singapore, Singapore.

出版信息

Eur J Neurol. 2011 Mar;18(3):519-26. doi: 10.1111/j.1468-1331.2010.03210.x. Epub 2010 Sep 14.

DOI:10.1111/j.1468-1331.2010.03210.x

PMID:20840378

Abstract

BACKGROUND

This study was carried out to evaluate the economic burden of Parkinson's disease (PD) and factors independently associated with individual components of total cost in Singapore.

METHODS

A consecutive sample of 195 patients with PD (mean age: 68.2, men: 51.8%) attending a tertiary neuroscience clinic were identified and interviewed using standardized questionnaires including a financial burden questionnaire, two Health Related Quality of Life (HRQoL) questionnaires and the Beck Depression Inventory questionnaire.

RESULTS

Annual total cost of PD from a societal perspective was SGD11345 (USD10129) per patient, with direct cost accounted for 38.5% and indirect cost 61.5%. The main cost components for direct medical cost, direct non-medical cost, and indirect cost was pharmacotherapy (50.4%), home care (76.1%), and productivity loss (97.9%), respectively. In multiple linear regression analysis, higher education, younger age and longer duration of PD were associated with higher total cost.

CONCLUSIONS

Parkinson's disease exerts a considerable burden on patients, health care system and society in Singapore. As productivity loss accounts for a large share of the economic burden imposed by PD, treatments and health care programmes with potential for returning patients to higher productivity are urgently needed.

摘要

背景

本研究旨在评估新加坡帕金森病（PD）的经济负担，以及与总费用各组成部分相关的独立因素。

方法

从一家三级神经科学诊所连续选取了 195 名 PD 患者（平均年龄：68.2 岁，男性占 51.8%），并通过标准化问卷对其进行访谈，问卷内容包括经济负担问卷、两份健康相关生活质量问卷和贝克抑郁量表。

结果

从社会角度来看，每位 PD 患者的年度总费用为 11345 新加坡元（10129 美元），直接成本占 38.5%，间接成本占 61.5%。直接医疗成本、直接非医疗成本和间接成本的主要成本构成分别为药物治疗（50.4%）、家庭护理（76.1%）和生产力损失（97.9%）。多元线性回归分析显示，较高的教育程度、较年轻的年龄和较长的 PD 病程与较高的总费用相关。