Department of Anesthesia and Intensive Care, Hospital for Children and Adolescents, Helsinki University Central Hospital, Finland.
Acta Anaesthesiol Scand. 2010 Nov;54(10):1276-81. doi: 10.1111/j.1399-6576.2010.02307.x. Epub 2010 Sep 14.
There is a lack of data on the outcome of cardiopulmonary bypass (CPB) rewarming of hypothermic children with cardiac arrest following drowning.
To retrospectively analyze single-center outcome of drowning victims treated with CPB.
This retrospective study included all hypothermic drowning victims admitted to the Hospital for Children and Adolescents with attempted resuscitation on CPB between 1994 and 2008 inclusive. Median sternotomy and cannulation of the ascending aorta and the right atrium for CPB were performed on all victims.
Nine hypothermic drowning victims, comprising five boys and four girls, with a median age of 3.8 years (range, 1.5-10 years). The median submersion time was 38 min (range, 5-75 min) and the median water temperature was 6.5 °C (range, 0.2-16.5 °C). The median core temperature was 21.9 °C (range 17.7-32.8 °C) at arrival to the hospital. All nine children were able to be weaned from CPB. Only one child, with mild to moderate neurological deficit, became a long-term survivor. She was slowly rewarmed up to 33 °C with CPB and kept in mild hypothermia for 48 h.
Large numbers of submerged children can be primarily resuscitated with CPB. Unfortunately, many of them will decease from severe hypoxic brain injury. Slow rewarming with CPB may improve the likelihood of a better neurological outcome.
目前缺乏关于心肺复苏(CPB)复温在溺水后心脏骤停的低体温儿童的结果数据。
回顾性分析使用 CPB 治疗溺水者的单中心结果。
本回顾性研究纳入了 1994 年至 2008 年间在儿童医院接受 CPB 复苏治疗的所有低体温溺水受害者。所有患者均行正中胸骨切开术和升主动脉及右心房插管行 CPB。
9 例低体温溺水受害者,包括 5 名男孩和 4 名女孩,中位年龄为 3.8 岁(范围 1.5-10 岁)。中位淹溺时间为 38 分钟(范围 5-75 分钟),中位水温为 6.5°C(范围 0.2-16.5°C)。到达医院时,中位数核心温度为 21.9°C(范围 17.7-32.8°C)。9 例患儿均能成功脱机 CPB。仅有 1 例存在轻度至中度神经功能缺损的患儿成为长期幸存者。她在 CPB 下缓慢复温至 33°C,并保持轻度低温 48 小时。
大量溺水儿童可以通过 CPB 进行初步复苏。不幸的是,其中许多人会因严重缺氧性脑损伤而死亡。CPB 缓慢复温可能会提高更好的神经结局的可能性。