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烟曲霉关节感染:综述。

Aspergillus fumigatus joint infection: a review.

机构信息

Rheumatology, Intensive Care and Hematology Section, Hospital Israelita Albert Einstein, Sao Paulo, Brazil.

出版信息

Semin Arthritis Rheum. 2011 Jun;40(6):580-4. doi: 10.1016/j.semarthrit.2010.07.007. Epub 2010 Sep 16.

DOI:10.1016/j.semarthrit.2010.07.007
PMID:20843541
Abstract

OBJECTIVES

To describe a case of joint infection by Aspergillus fumigatus in a unusual site (sacroiliac) and perform a systematic review of such cases described in the literature.

METHODS

We performed a Medline search of the cases of fungal joint of Aspergillus fumigatus in the period ranging from 1970 to 2009.

RESULTS

Following PRISMA Guidelines, 15 cases including ours were reported during this period. Stem cell and solid organ transplantation, hematologic malignancy, and intra-articular steroids injection were the medical conditions found in such patients. The knee followed by the shoulder were the joints more affected. In the cases where synovial fluid analyses were reported, elevated cell count numbers could be found with a predominance of polymorphonuclear neutrophils.

CONCLUSIONS

Fungal joint arthritis is a rare clinical disease most frequently present in immuno-incompetent patients. Rheumatologists should be aware of this condition, where early diagnosis can be associated with good prognosis.

摘要

目的

描述一例烟曲霉引起的关节感染(发生在不常见的部位-骶髂关节),并对文献中描述的此类病例进行系统回顾。

方法

我们对 1970 年至 2009 年间烟曲霉真菌性关节病例进行了 Medline 检索。

结果

根据 PRISMA 指南,在此期间共报告了 15 例包括我们的病例。干细胞和实体器官移植、血液恶性肿瘤和关节内类固醇注射是这些患者的医疗条件。受影响最严重的关节是膝关节,其次是肩关节。在报告了关节滑液分析的病例中,可以发现细胞计数升高,以多形核中性粒细胞为主。

结论

真菌性关节关节炎是一种罕见的临床疾病,最常发生于免疫功能低下的患者。风湿病学家应该意识到这种情况,早期诊断可以与良好的预后相关。

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