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一名免疫功能正常的中年女性，患有未确诊的复发性肺曲霉病，出现髋关节曲霉性脓毒性关节炎。

Aspergillus Septic Arthritis of the Hip in an Immunocompetent Middle-aged Female with Undiagnosed Recurrent Pulmonary Aspergillosis.

作者信息

Yoon Pil Whan, Song Joo Ho, Yoon Kang Sup, Chang Jae Suk, Kim Hee Joong, Rhyu Kee Hyung

机构信息

Department of Orthopaedic Surgery, Asan Medical Center, Seoul, Korea.

Department of Orthopaedic Surgery, SMG-SNU Boramae Medical Center, Seoul, Korea.

出版信息

Hip Pelvis. 2015 Sep;27(3):196-200. doi: 10.5371/hp.2015.27.3.196. Epub 2015 Sep 30.

DOI:10.5371/hp.2015.27.3.196
PMID:27536626
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4972727/
Abstract

We present a case of Aspergillus septic hip arthritis in an immunocompetent patient with undiagnosed recurrent pulmonary aspergillosis who underwent arthroscopic surgery. Biopsy specimens of synovium revealed fungal hyphae, confirming Aspergillus infection. Aspergillus septic hip arthritis can occur in immunocompetent patients, and arthroscopy can be a noninvasive surgical option in these cases.

摘要

我们报告一例免疫功能正常但患有未确诊复发性肺曲霉病的患者发生曲霉性化脓性髋关节炎，并接受了关节镜手术。滑膜活检标本显示有真菌菌丝，证实为曲霉感染。曲霉性化脓性髋关节炎可发生于免疫功能正常的患者，在这些病例中关节镜检查可以作为一种非侵入性的手术选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5286/4972727/1f9593877d81/hp-27-196-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5286/4972727/481139f77915/hp-27-196-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5286/4972727/f17e6e077193/hp-27-196-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5286/4972727/4275a0e91132/hp-27-196-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5286/4972727/1f9593877d81/hp-27-196-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5286/4972727/481139f77915/hp-27-196-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5286/4972727/f17e6e077193/hp-27-196-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5286/4972727/4275a0e91132/hp-27-196-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5286/4972727/1f9593877d81/hp-27-196-g004.jpg

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本文引用的文献

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Aspergillus fumigatus joint infection: a review.烟曲霉关节感染：综述。
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2
Articular aspergillosis: case report and review of the literature.关节曲霉病：病例报告及文献复习。
Int J Infect Dis. 2010 May;14(5):e433-5. doi: 10.1016/j.ijid.2009.05.012. Epub 2009 Aug 4.
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Management of Aspergillus osteomyelitis: report of failure of liposomal amphotericin B and response to voriconazole in an immunocompetent host and literature review.
Med Mycol. 2022 Aug 3;60(8). doi: 10.1093/mmy/myac052.
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Native Joint Infections by Species.按菌种分类的天然关节感染
Diagnostics (Basel). 2021 Dec 11;11(12):2335. doi: 10.3390/diagnostics11122335.
曲霉性骨髓炎的治疗：免疫功能正常宿主中脂质体两性霉素B治疗失败及伏立康唑治疗反应的报告与文献综述
Eur J Clin Microbiol Infect Dis. 2003 May;22(5):277-83. doi: 10.1007/s10096-003-0909-3. Epub 2003 May 7.