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氯氮平在妊娠期的应用。

Clozapine in pregnancy.

机构信息

Lecturer, Department of Psychiatry, PGIMS, Rohtak; mailing address: 122/8, Shivaji Colony, Rohtak 124001, Haryana; e-mail:

出版信息

Indian J Psychiatry. 2006 Jul;48(3):196-7. doi: 10.4103/0019-5545.31586.

DOI:10.4103/0019-5545.31586
PMID:20844653
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2932993/
Abstract

This report describes the case of a woman with treatment-resistant schizophrenia who became pregnant while being treated successfully with clozapine. Possible risks associated with continuation of clozapine during pregnancy are discussed.

摘要

本报告描述了一例治疗抵抗性精神分裂症女性患者在成功使用氯氮平治疗期间怀孕的案例。讨论了在怀孕期间继续使用氯氮平可能带来的风险。

相似文献

1
Clozapine in pregnancy.氯氮平在妊娠期的应用。
Indian J Psychiatry. 2006 Jul;48(3):196-7. doi: 10.4103/0019-5545.31586.
2
Clozapine use in two women with schizophrenia during pregnancy.两名精神分裂症女性在孕期使用氯氮平的情况。
J Psychopharmacol. 2008 Jan;22(1):111-3. doi: 10.1177/0269881107079171.
3
Pregnancy of a patient treated with clozapine.接受氯氮平治疗的患者怀孕。
Psychiatr Serv. 1998 Aug;49(8):1081-3. doi: 10.1176/ps.49.8.1081.
4
A review of the safety of clozapine during pregnancy and lactation.氯氮平在孕期及哺乳期的安全性综述。
Arch Womens Ment Health. 2017 Feb;20(1):1-9. doi: 10.1007/s00737-016-0670-0. Epub 2016 Oct 4.
5
Continuation Electroconvulsive Therapy for Patients With Clozapine-Resistant Schizophrenia: A Pilot Study.氯氮平难治性精神分裂症患者的延续电抽搐治疗:一项初步研究。
J ECT. 2019 Sep;35(3):156-160. doi: 10.1097/YCT.0000000000000588.
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Safety of clozapine in a woman with triplet pregnancy: A case report.氯氮平在一位三胞胎妊娠女性中的安全性:病例报告
Asian J Psychiatr. 2016 Aug;22:67-8. doi: 10.1016/j.ajp.2016.04.009. Epub 2016 May 13.
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Quetiapine XR-induced neutropenia: is a clozapine trial still possible for treatment-resistant schizophrenia? A case report.喹硫平缓释片所致中性粒细胞减少症:对于难治性精神分裂症,氯氮平试验是否仍可行?一例病例报告。
Early Interv Psychiatry. 2015 Apr;9(2):151-5. doi: 10.1111/eip.12134. Epub 2014 Apr 1.
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Neonatal death following clozapine self-poisoning in late pregnancy: an unusual case report.妊娠晚期氯氮平自服中毒后新生儿死亡:一例罕见病例报告。
Forensic Sci Int. 2007 Aug 24;171(1):e5-e10. doi: 10.1016/j.forsciint.2007.04.216. Epub 2007 Jun 1.
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[Clozapine-resistant schizophrenia related to an increased metabolism and benefit of fluvoxamine: four case reports].[与代谢增加及氟伏沙明获益相关的氯氮平难治性精神分裂症:4例报告]
Encephale. 2007 Oct;33(5):811-8. doi: 10.1016/j.encep.2007.01.005.
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Young patient with treatment-resistant schizophrenia drastically improved by combination of clozapine and maintenance electroconvulsive therapy: a case report.氯氮平与维持性电休克治疗联合使用使难治性精神分裂症年轻患者病情大幅改善:一例报告
Int Med Case Rep J. 2019 Jun 21;12:185-188. doi: 10.2147/IMCRJ.S198124. eCollection 2019.

引用本文的文献

1
Use of Antipsychotic Drugs During Pregnancy.孕期使用抗精神病药物。
Curr Treat Options Psychiatry. 2019 Mar;6(1):17-31. doi: 10.1007/s40501-019-0165-5. Epub 2019 Jan 30.
2
Mood stabilizers in pregnancy and lactation.孕期及哺乳期的心境稳定剂
Indian J Psychiatry. 2015 Jul;57(Suppl 2):S308-23. doi: 10.4103/0019-5545.161498.
3
Women psychiatrists in India: A reflection of their contributions.印度女精神科医生:她们贡献的写照。
Indian J Psychiatry. 2010 Jan;52(Suppl 1):S396-401. doi: 10.4103/0019-5545.69277.
4
Research in child and adolescent psychiatry in India.印度儿童和青少年精神病学研究。
Indian J Psychiatry. 2010 Jan;52(Suppl 1):S219-23. doi: 10.4103/0019-5545.69235.
5
Indian research: Focus on clozapine.印度研究:聚焦氯氮平。
Indian J Psychiatry. 2010 Apr;52(2):168-73. doi: 10.4103/0019-5545.64592.
6
Clozapine: Current perspective.氯氮平:现状。
Indian J Psychiatry. 2007 Oct;49(4):271-6. doi: 10.4103/0019-5545.37668.

本文引用的文献

1
Clozapine and pregnancy.氯氮平与妊娠
J Clin Psychiatry. 2003 Jul;64(7):850. doi: 10.4088/jcp.v64n0718e.
2
The reproductive safety profile of mood stabilizers, atypical antipsychotics, and broad-spectrum psychotropics.心境稳定剂、非典型抗精神病药物及广谱精神药物的生殖安全性概况。
J Clin Psychiatry. 2002;63 Suppl 4:42-55.
3
Pregnancy of a patient treated with clozapine.接受氯氮平治疗的患者怀孕。
Psychiatr Serv. 1998 Aug;49(8):1081-3. doi: 10.1176/ps.49.8.1081.
4
Clozapine and associated diabetes mellitus.氯氮平与相关的糖尿病
J Clin Psychiatry. 1997 Mar;58(3):108-11. doi: 10.4088/jcp.v58n0304.
5
Clozapine concentrations in maternal and fetal plasma, amniotic fluid, and breast milk.氯氮平在母体和胎儿血浆、羊水及母乳中的浓度。
Am J Psychiatry. 1994 Jun;151(6):945. doi: 10.1176/ajp.151.6.945.
6
Pregnancy and clozapine.妊娠与氯氮平
Am J Psychiatry. 1993 Jan;150(1):168-9. doi: 10.1176/ajp.150.1.168a.