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接受氯氮平治疗的患者怀孕。

Pregnancy of a patient treated with clozapine.

作者信息

Dickson R A, Hogg L

机构信息

Department of Psychiatry at the University of Calgary, Alberta, Canada.

出版信息

Psychiatr Serv. 1998 Aug;49(8):1081-3. doi: 10.1176/ps.49.8.1081.

DOI:10.1176/ps.49.8.1081
PMID:9712217
Abstract

The authors describe the case of a patient with treatment-resistant schizophrenia who became pregnant after switching from conventional neuroleptic medications to clozapine, an atypical antipsychotic medication that does not cause hyperprolactinemia. Gestational diabetes, possibly exacerbated by clozapine, complicated management of her pregnancy. Comprehensive community support and psychiatric rehabilitation, combined with a positive response to clozapine, contributed to satisfying the patient's goal of having a healthy baby and being able to take the baby home to live with her and her husband.

摘要

作者描述了一名难治性精神分裂症患者的病例,该患者在从传统抗精神病药物换用氯氮平(一种不会引起高催乳素血症的非典型抗精神病药物)后怀孕。妊娠糖尿病可能因氯氮平而加重,使她的孕期管理变得复杂。全面的社区支持和精神康复,再加上对氯氮平的积极反应,有助于实现患者生下健康宝宝并能将宝宝带回家与她和丈夫一起生活的目标。

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Pregnancy of a patient treated with clozapine.接受氯氮平治疗的患者怀孕。
Psychiatr Serv. 1998 Aug;49(8):1081-3. doi: 10.1176/ps.49.8.1081.
2
Implications for anaesthesia in a patient established on clozapine treatment.氯氮平治疗患者的麻醉相关问题
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Neuroleptic-resistant schizophrenia treated with clozapine and ECT.使用氯氮平和电休克治疗难治性精神分裂症。
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A review of the safety of clozapine during pregnancy and lactation.氯氮平在孕期及哺乳期的安全性综述。
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Ment Health Clin. 2022 Jan 21;12(1):37-44. doi: 10.9740/mhc.2022.01.037. eCollection 2022 Jan.
2
Clozapine: An Updated Overview of Pharmacogenetic Biomarkers, Risks, and Safety-Particularities in the Context of COVID-19.氯氮平:COVID-19背景下药物遗传生物标志物、风险及安全性特点的最新综述
Brain Sci. 2020 Nov 11;10(11):840. doi: 10.3390/brainsci10110840.
3
Clozapine Use During Pregnancy and Lactation: A Case-Series Report.
孕期及哺乳期使用氯氮平:病例系列报告
Front Pharmacol. 2018 Mar 27;9:264. doi: 10.3389/fphar.2018.00264. eCollection 2018.
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Mood stabilizers in pregnancy and lactation.孕期及哺乳期的心境稳定剂
Indian J Psychiatry. 2015 Jul;57(Suppl 2):S308-23. doi: 10.4103/0019-5545.161498.
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Psychiatry (Edgmont). 2005 Aug;2(8):36-44.
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Clozapine in pregnancy.氯氮平在妊娠期的应用。
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Second-generation (atypical) antipsychotics and metabolic effects: a comprehensive literature review.第二代(非典型)抗精神病药物与代谢效应:一项全面的文献综述
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