Department of Child and Adolescent Psychiatry/Psychotherapy, University Hospital Ulm, Steinhövelstrasse 5, 89075, Ulm, Germany.
Qual Life Res. 2011 Mar;20(2):225-36. doi: 10.1007/s11136-010-9739-9. Epub 2010 Sep 16.
To compare the general and health-related life satisfaction (LS) in long-term survivors of adolescent cancer with a community sample and to identify medical and psychosocial factors associated with LS.
LS of 820 survivors (age M = 30.4 ± 6.0 years; time since diagnosis M = 13.7 ± 6.0 years) was assessed with the Questions on Life Satisfaction (FLZ(M)) and compared to an age- and sex-matched community sample. The effects of medical, psychological, and socio-demographical factors on the survivors' general and health-related LS were investigated by means of multiple regression analyses.
Survivors were significantly less satisfied than the comparison group in terms of both their general (P < .001, d = -.35) and health-related (P < .001, d = -.47) life. Somatic late effects, symptoms of depression and anxiety, and less posttraumatic growth were associated with impaired general and health-related LS. Moreover, being married contributed significantly to higher general LS.
Adult survivors of cancer with onset during adolescence are experiencing less LS than the general population. Long-term routine follow-up visits are recommended to identify persisting effects of cancer survival on LS and to provide support for those with special needs. Physicians need to pay special attention to potential risk factors such as psychological distress, somatic late effects, persistent psychological distress, and a lack of posttraumatic growth, which are negatively correlated with LS.
比较青少年癌症长期幸存者的一般生活满意度和健康相关生活满意度(LS),并确定与 LS 相关的医学和心理社会因素。
使用生活满意度问卷(FLZ(M))评估 820 名幸存者(年龄 M = 30.4 ± 6.0 岁;诊断后时间 M = 13.7 ± 6.0 年)的 LS,并将其与年龄和性别匹配的社区样本进行比较。通过多元回归分析研究了医学、心理和社会人口因素对幸存者一般和健康相关 LS 的影响。
与对照组相比,幸存者在一般生活(P <.001,d = -.35)和健康相关生活(P <.001,d = -.47)方面的满意度明显较低。躯体迟发性效应、抑郁和焦虑症状以及较少的创伤后成长与一般和健康相关 LS 受损有关。此外,已婚对一般 LS 的提高有显著贡献。
青少年期发病的癌症成年幸存者的 LS 低于一般人群。建议长期进行常规随访,以确定癌症生存对 LS 的持续影响,并为有特殊需求的人提供支持。医生需要特别注意潜在的风险因素,如心理困扰、躯体迟发性效应、持续的心理困扰和缺乏创伤后成长,这些因素与 LS 呈负相关。