Department of Medicine, Ålesund Hospital, Sunnmøre Hospital Trust, Ålesund, Norway.
Eur J Heart Fail. 2010 Nov;12(11):1247-52. doi: 10.1093/eurjhf/hfq156. Epub 2010 Sep 16.
To evaluate the quality of life in heart failure (HF) outpatients attending multidisciplinary disease management programmes at HF clinics in Norwegian hospitals.
Data from HF patients at 24 hospital outpatient clinics were entered in a common database; The Norwegian Heart Failure Registry. Quality of life assessment was done using Minnesota Living with Heart Failure Questionnaire (MLHF). The quality of life assessment was optional at each hospital and was done both at initial evaluation and after 6 months of stable follow-up. A total of 3632 patients were included in the registry and 1778 patients had at least one assessment of quality of life. The mean MLHF score improved significantly from 2.1 at the initial evaluation to 1.4 six months after leaving the clinic (P < 0.001). There was a significant difference in MLHF score between hospitals and baseline MLHF score was significantly associated with NYHA functional class, hospitalizations 6 months before entering the registry, and brain natriuretic peptide; and inversely related to age and systolic blood pressure. Minnesota Living with Heart Failure score was an independent predictor of mortality in this population.
Quality of life assessed with MLHF improved after follow-up at outpatient HF clinics. Minnesota Living with Heart Failure score was significantly related to functional status, laboratory and demographic variables, and was an important predictor of prognosis.
评估在挪威医院的心力衰竭（HF）诊所参加多学科疾病管理计划的门诊患者的生活质量。
将 24 家医院门诊诊所的 HF 患者的数据输入到一个共同的数据库中；挪威心力衰竭登记处。使用明尼苏达州心力衰竭生活质量问卷（MLHF）进行生活质量评估。每个医院都可以选择进行生活质量评估，并且在初始评估和稳定随访 6 个月后都可以进行评估。该登记处共纳入 3632 例患者，其中 1778 例患者至少有一次生活质量评估。MLHF 评分从初始评估时的 2.1 显著改善至离开诊所 6 个月后的 1.4（P < 0.001）。各医院之间的 MLHF 评分存在显著差异，基线 MLHF 评分与 NYHA 功能分级、进入登记处前 6 个月的住院次数以及脑钠肽显著相关；与年龄和收缩压呈负相关。在该人群中，MLHF 评分是死亡率的独立预测因子。
HF 门诊随访后，用 MLHF 评估的生活质量得到改善。MLHF 评分与功能状态、实验室和人口统计学变量显著相关，是预后的重要预测因子。
