与中枢神经系统罗道尔夫病相关的结膜下肿块。
Subconjunctival masses associated with central nervous system rosai-dorfman disease.
机构信息
Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miami, FL, USA.
出版信息
Cornea. 2011 Feb;30(2):237-40. doi: 10.1097/ICO.0b013e3181e4570c.
PURPOSE
To describe a case of subconjunctival masses with multiple intracranial masses diagnosed as Rosai-Dorfman disease by biopsy.
METHODS
Case report.
RESULTS
A 25-year-old white man presented with bilateral subconjunctival masses, left optic nerve pallor, and posterior segment changes suggestive of regressed choroidal disease. Systemic evaluation was instituted including blood testing, neuroimaging, brain biopsy, and biopsy of the left subconjunctival mass. Pathologic analysis of the brain and subconjunctival mass biopsies revealed Rosai-Dorfman disease.
CONCLUSIONS
The authors present a case of extensive extranodal involvement of Rosai-Dorfman of the eye and the central nervous system.
目的
通过活检描述一例诊断为罗萨达-多夫曼病的眼附属器肿块伴多发颅内肿块病例。
方法
病例报告。
结果
一名 25 岁白人男性因双侧结膜下肿块、左眼视神经苍白和后节改变（提示脉络膜疾病消退）就诊。进行了全身评估，包括血液检查、神经影像学、脑活检和左眼结膜下肿块活检。脑和结膜下肿块活检的病理分析显示罗萨达-多夫曼病。
结论
作者报告了一例眼和中枢神经系统广泛的罗萨达-多夫曼病的结外受累病例。
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