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罗萨伊-多夫曼病：春季角结膜炎患者的孤立性眼球表面肿物

Rosai-Dorfman disease: Isolated epibulbar mass in patient with vernal keratoconjunctivitis.

作者信息

Alharbi Saad S, Edward Deepak P

机构信息

Anterior Segment, King Khaled Eye Specialist Hospital, Saudi Arabia.

Pathology and Glaucoma, King Khaled Eye Specialist Hospital, Saudi Arabia.

出版信息

Saudi J Ophthalmol. 2020 Nov 22;34(1):53-55. doi: 10.4103/1319-4534.301290. eCollection 2020 Jan-Mar.

DOI:10.4103/1319-4534.301290
PMID:33542989
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7849862/
Abstract

A 29-year-old male known case of vernal keratoconjunctivitis (VKC) presented with 5-month history of a rapidly growing mass on the temporal aspect of the right cornea. The 9 × 9 mm epibulbar lesion was excised and histologically showed features of extranodal Rosai Dorfman disease (RDD) with emperipolesis of eosinophils. The lesion did not recur following excision. The association of RDD with VKC has not been previously reported; however, the causal relationship remains unclear.

摘要

一名29岁的男性，已知患有春季角结膜炎（VKC），右眼角颞侧有一个迅速生长的肿物，病程5个月。切除了这个9×9毫米的眼球表面病变，组织学检查显示为结外Rosai-Dorfman病（RDD）伴嗜酸性粒细胞的入胞现象。切除后病变未复发。RDD与VKC的关联此前未见报道；然而，因果关系仍不明确。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8bc/7849862/62f4f8e6d84f/SJO-34-53-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8bc/7849862/7dde842fc605/SJO-34-53-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8bc/7849862/62f4f8e6d84f/SJO-34-53-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8bc/7849862/7dde842fc605/SJO-34-53-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8bc/7849862/62f4f8e6d84f/SJO-34-53-g002.jpg

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本文引用的文献

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Subconjunctival masses associated with central nervous system rosai-dorfman disease.与中枢神经系统罗道尔夫病相关的结膜下肿块。
Cornea. 2011 Feb;30(2):237-40. doi: 10.1097/ICO.0b013e3181e4570c.
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Extranodal Rosai-Dorfman disease presenting as an isolated epibulbar mass.表现为孤立性眼球表面肿物的结外Rosai-Dorfman病
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Sinus histiocytosis with massive lymphadenopathy. A newly recognized benign clinicopathological entity.伴有巨大淋巴结病的窦性组织细胞增多症。一种新认识的良性临床病理实体。
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Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease): review of the entity.伴有巨大淋巴结病的窦组织细胞增生症（罗萨伊-多夫曼病）：该实体的综述
Semin Diagn Pathol. 1990 Feb;7(1):19-73.
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Rosai-Dorfman disease of soft tissue.软组织罗萨伊-多夫曼病
Am J Surg Pathol. 1992 Feb;16(2):122-9. doi: 10.1097/00000478-199202000-00004.
10
Detection of human herpesvirus 6 in tissues involved by sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease).在伴有巨大淋巴结病的窦性组织细胞增生症（罗萨伊-多夫曼病）累及的组织中检测人疱疹病毒6 。
J Infect Dis. 1992 Aug;166(2):291-5. doi: 10.1093/infdis/166.2.291.