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因眼睑松弛综合征导致的局部麻醉剂滥用性角膜炎。

Topical anesthetic abuse keratitis secondary to floppy eyelid syndrome.

机构信息

Department of Ophthalmology, Assaf Harofeh Medical Center, Tel-Aviv University, Tel-Aviv, Israel.

出版信息

Cornea. 2011 Jan;30(1):105-6. doi: 10.1097/ICO.0b013e3181e458af.

DOI:10.1097/ICO.0b013e3181e458af
PMID:20847677
Abstract

PURPOSE

To report the diagnosis and management of a patient with chronic ophthalmic topical anesthetic abuse and floppy eyelid syndrome.

METHODS

We describe the case of a 47-year-old man suffering from persistent bilateral ocular irritation and chronic corneal erosions.

RESULTS

The patient was hospitalized in our ophthalmology department and underwent thorough ophthalmic, systemic, and psychiatric evaluation. Chronic topical anesthetic abuse was discovered. Removal of abused drops and copious lubricating treatment lead to partial improvement further permitting diagnosis of floppy eyelid syndrome. Definitive surgical treatment by horizontal eyelid tightening combined with continuous lubrication resulted in remission of symptoms.

CONCLUSIONS

Uncommon conditions may coexist in 1 patient. In this case, floppy eyelid syndrome resulted in topical anesthetic abuse. Ophthalmologists should keep both these conditions in mind when treating patients with otherwise unexplained chronic persistent corneal erosions.

摘要

目的

报告 1 例慢性眼部局部麻醉剂滥用伴眼睑下垂综合征患者的诊断和治疗方法。

方法

我们描述了 1 例 47 岁男性患者,其患有持续性双侧眼部刺激和慢性角膜糜烂。

结果

患者因慢性局部麻醉剂滥用被收入我院眼科。经全面眼科、系统和精神科评估后发现,该患者患有慢性局部麻醉剂滥用。停止使用滥用的滴眼剂并进行大量润滑治疗后,症状部分改善,从而进一步诊断为眼睑下垂综合征。通过水平眼睑收紧联合持续润滑的确定性手术治疗使症状缓解。

结论

在 1 例患者中可能会同时存在不常见的病症。在本例中,眼睑下垂综合征导致了局部麻醉剂滥用。当眼科医生治疗其他原因不明的慢性持续性角膜糜烂的患者时,应牢记这两种情况。

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Topical anesthetic abuse keratitis secondary to floppy eyelid syndrome.因眼睑松弛综合征导致的局部麻醉剂滥用性角膜炎。
Cornea. 2011 Jan;30(1):105-6. doi: 10.1097/ICO.0b013e3181e458af.
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Topical anesthetic abuse ring keratitis: report of four cases.局部麻醉药滥用性角膜炎:4例报告
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Clinical findings in patients with topical anaesthetic abuse keratitis: a report of five cases.表面麻醉剂滥用性角膜炎患者的临床发现:5例报告
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[A clinico-pathological case report of necrotizing ulcerating keratopathy due to topical anaesthetic abuse].[一例因滥用局部麻醉剂导致坏死性溃疡性角膜病变的临床病理病例报告]
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Toxic keratopathy due to abuse of topical anesthetic drugs.滥用局部麻醉药物所致的中毒性角膜病。
Cutan Ocul Toxicol. 2010 Jun;29(2):105-9. doi: 10.3109/15569521003631752.
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Corneal anesthetic abuse and Candida keratitis.角膜麻醉剂滥用与念珠菌性角膜炎
Ophthalmology. 1996 Jan;103(1):37-40. doi: 10.1016/s0161-6420(96)30735-5.
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Ring keratitis from topical anaesthetic misuse.因局部麻醉剂使用不当导致的环形角膜炎。
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Topical anesthetic abuse and ring keratitis.局部麻醉药滥用与环形角膜炎
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Topical anesthetic abuse after radial keratotomy.放射状角膜切开术后局部麻醉药滥用
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Br J Ophthalmol. 1986 Mar;70(3):202-4. doi: 10.1136/bjo.70.3.202.

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Adverse Reactions from Topical Ophthalmic Anesthetic Abuse.局部眼科麻醉剂滥用引起的不良反应。
J Ophthalmic Vis Res. 2022 Nov 29;17(4):470-478. doi: 10.18502/jovr.v17i4.12297. eCollection 2022 Oct-Dec.
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Corneal Thickness Response after Anesthetic Eye Drops: Our Own Results and Meta-Analysis.麻醉滴眼液后角膜厚度的反应:我们自己的结果和荟萃分析。
Biomed Res Int. 2018 Mar 5;2018:4743721. doi: 10.1155/2018/4743721. eCollection 2018.
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Topical ocular anesthetic abuse among Iranian welders: time for action.伊朗焊工中局部眼部麻醉剂滥用问题:是采取行动的时候了。
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