白细胞介素-9 的细胞来源和免疫功能。
Cellular sources and immune functions of interleukin-9.
机构信息
Department of Microbiology and Immunology, Dartmouth Medical School, Lebanon, New Hampshire 03756, USA.
出版信息
Nat Rev Immunol. 2010 Oct;10(10):683-7. doi: 10.1038/nri2848. Epub 2010 Sep 17.
Abstract
Interleukin-9 (IL-9) has attracted renewed interest owing to the identification of its expression by multiple T helper (T(H)) cell subsets, including T(H)2 cells, T(H)9 cells, T(H)17 cells and regulatory T (T(Reg)) cells. Here, we provide a broad overview of the conditions that are required for cells to produce IL-9 and describe the cellular targets and nature of the immune responses that are induced by IL-9.
摘要
白细胞介素-9（IL-9）因其在多种辅助性 T 细胞（T(H)）亚群中的表达而受到重新关注，包括 T(H)2 细胞、T(H)9 细胞、T(H)17 细胞和调节性 T（T(Reg)）细胞。在此，我们提供了细胞产生 IL-9 所需条件的广泛概述，并描述了 IL-9 诱导的细胞靶标和免疫反应的性质。
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