University of Montana, Missoula, 59812, USA.
Nat Rev Genet. 2010 Oct;11(10):697-709. doi: 10.1038/nrg2844.
We will soon have complete genome sequences from thousands of species, as well as from many individuals within species. This coming explosion of information will transform our understanding of the amount, distribution and functional significance of genetic variation in natural populations. Now is a crucial time to explore the potential implications of this information revolution for conservation genetics and to recognize limitations in applying genomic tools to conservation issues. We identify and discuss those problems for which genomics will be most valuable for curbing the accelerating worldwide loss of biodiversity. We also provide guidance on which genomics tools and approaches will be most appropriate to use for different aspects of conservation.
我们很快将获得数千个物种以及每个物种内许多个体的完整基因组序列。这一信息爆炸将彻底改变我们对自然种群中遗传变异的数量、分布和功能意义的理解。现在是探索这一信息革命对保护遗传学的潜在影响并认识到将基因组工具应用于保护问题的局限性的关键时期。我们确定并讨论了那些最有价值的基因组学方法，这些方法将有助于遏制全球范围内生物多样性的加速丧失。我们还就不同保护方面最适合使用哪些基因组学工具和方法提供了指导。
