SPECT/CT 用于头颈部黑色素瘤前哨淋巴结定位。
SPECT/CT for sentinel lymph node mapping in head and neck melanoma.
机构信息
Department of Nuclear Medicine, Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.
出版信息
Head Neck. 2011 Jan;33(1):1-6. doi: 10.1002/hed.21392.
BACKGROUND
The additional value of single photon emission computed tomography with CT (SPECT/CT) for detection and localization of sentinel nodes in patients with a melanoma of the head and neck was determined.
METHODS
Thirty-eight patients received conventional lymphoscintigraphy followed by hybrid SPECT/CT. The number of sentinel nodes visualized and anatomic information provided were analyzed. Changes in surgical approach due to additional information from the SPECT/CT were evaluated in 20 patients.
RESULTS
SPECT/CT visualized a mean of 2.6 sentinel nodes per patient (range, 1-6). SPECT/CT depicted an additional sentinel node in 16% of the patients and clearly showed the anatomic location of the hot nodes in all patients. The surgical approach was adjusted on the basis of SPECT/CT images in 11 patients (55%).
CONCLUSION
SPECT/CT visualizes more sentinel nodes than conventional images and shows their anatomic location. SPECT/CT is recommended in patients with a melanoma in the head or neck.
背景
本研究旨在确定单光子发射计算机断层扫描与 CT（SPECT/CT）联合应用对头颈部黑色素瘤患者前哨淋巴结检测和定位的附加价值。
方法
38 例患者行常规淋巴闪烁显像后行 SPECT/CT 融合显像。分析了 SPECT/CT 检测到的前哨淋巴结数量和提供的解剖学信息。对 20 例患者评估了 SPECT/CT 提供的附加信息对手术方式的影响。
结果
SPECT/CT 平均显示每位患者 2.6 个前哨淋巴结（范围，1-6）。SPECT/CT 在 16%的患者中显示了额外的前哨淋巴结，并在所有患者中清楚地显示了热点淋巴结的解剖位置。根据 SPECT/CT 图像，11 例患者（55%）调整了手术方式。
结论
SPECT/CT 比常规图像能更准确地显示前哨淋巴结，并显示其解剖位置。建议对头颈部黑色素瘤患者行 SPECT/CT 检查。
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