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关于模式生物的编史学反思:或者说官僚主义可能如何限制我们对当代遗传学和基因组学的理解。

Historiographic reflections on model organisms: or how the mureaucracy may be limiting our understanding of contemporary genetics and genomics.

机构信息

School of History and Politics, Napier Building, The University of Adelaide, Adelaide SA 5005, Australia.

出版信息

Hist Philos Life Sci. 2010;32(1):91-104.

Abstract

Scholarship in the history of biology focused on model organisms has burgeoned along with the growth of the use of these organisms in genetic research in the closing decades of the 20th century. This paper draws on criticisms of model organism-based research, particularly the epistemological dangers of focus on a relatively limited number of species whose very development has become canalized through processes of standardization, to articulate the analogous historical pitfalls of these blinders for developing a fuller history of genetics and genomics.

摘要

生物学史中的学术研究主要以模式生物为研究对象,这种趋势随着 20 世纪最后几十年中这些生物在遗传研究中的广泛应用而蓬勃发展。本文借鉴了对基于模式生物的研究的批评,尤其是关注数量相对较少的物种所带来的认识论危险,这些物种的发展本身就通过标准化过程而变得定向化了,本文旨在阐明这些局限性类似的历史陷阱,以更全面地了解遗传学和基因组学的发展历史。

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