[2007 - 2008年山西省太原市婴幼儿病毒性腹泻流行病学特征分析]
[Analysis on epidemiologic characteristics of viral diarrhea among infants in Taiyuan, Shanxi province, 2007-2008].
作者信息
Lan Bei, Li Jie, Li Dan-Di, Jin Miao, Zhang Qing, Xu Zi-Qian, Cheng Wei-Xia, Xie Jin-Xin, Li Bo-Wen, Li Pei-Zhen, Duan Zhao-Jun
机构信息
College of Public Heath, Shanxi Medical University, Taiyuan 030001, China.
出版信息
Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 2010 Feb;24(1):8-10.
OBJECTIVE
To study the epidemiologic characteristics of virus-induced acute diarrhea in children under 5 years old in Taiyuan, Shanxi province.
METHODS
Stool specimens and clinical data were collected from 346 inpatients with acute diarrhea from children less than 5 years old. Rotavirus-positive specimens were identified by ELASA kit. Calicivirus and astrovirus were detected by reverse transcription-polymerase chain reaction (RT-PCR). Adenovirus was done by polymerase chain reaction (PCR).
RESULTS
Of the 346 specimens, the percentage of samples with Rotavirus, Calicivirus, Astrovirus, and Adenovirus was 40.8%, 7.5%, 6.4% and 3.2%. Among 141 rotavirus positive samples, serotype G1 (42.6%) was the predominant strain. More than 95% of viral diarrhea patients under hospitalization occurred among children younger than 2 years.
CONCLUSION
Rotavirus is the major pathogen contributing to the acute diarrhea. The disease generally peaks at autumn/winter. The predominant rotavirus strain circulated was G1P[8].
目的
研究山西省太原市5岁以下儿童病毒感染性急性腹泻的流行病学特征。
方法
收集346例5岁以下急性腹泻住院患儿的粪便标本及临床资料。采用酶联免疫吸附测定（ELASA）试剂盒鉴定轮状病毒阳性标本。采用逆转录聚合酶链反应（RT-PCR）检测杯状病毒和星状病毒。采用聚合酶链反应（PCR）检测腺病毒。
结果
346份标本中，轮状病毒、杯状病毒、星状病毒和腺病毒的检出率分别为40.8%、7.5%、6.4%和3.2%。在141份轮状病毒阳性样本中，G1型（42.6%）为主要毒株。住院的病毒感染性腹泻患儿中，95%以上发生在2岁以下儿童。
结论
轮状病毒是导致急性腹泻的主要病原体。该病一般在秋冬季节达到高峰。流行的主要轮状病毒毒株为G1P[8]。
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