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[嗜酸性粒细胞在支气管哮喘发病机制中的作用]

[Role of eosinophils in the pathogenesis of bronchial asthma].

作者信息

Zhikharev S S, Fedoseev G B, Kachanova T P, Razumovskaia T S, Plekhanova G I, Iamshchikova T Iu

出版信息

Ter Arkh. 1990;62(12):10-4.

PMID:2084904
Abstract

Analysis is made of the results of a comprehensive examination of 313 bronchial asthma patients. The examination included the revealing of the information relations of the absolute count of blood eosinophils, their changes after administration of a standard dose of adrenaline, the eosinophil count in sputum and bronchial secretion. Significant information relations with the build-up parameters, alterations in bronchial patency, a number of immunological and biochemical characteristics were discovered. Analysis of the measure of the information relation evidences the pathogenetic and prognostic role of eosinophils in bronchial asthma.

摘要

对313例支气管哮喘患者的综合检查结果进行了分析。检查包括揭示血液嗜酸性粒细胞绝对计数的信息关系、给予标准剂量肾上腺素后其变化、痰液和支气管分泌物中的嗜酸性粒细胞计数。发现了与体格参数、支气管通畅性改变、一些免疫和生化特征的重要信息关系。对信息关系测量的分析证明了嗜酸性粒细胞在支气管哮喘中的发病机制和预后作用。

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