Tomlinson Mathew J, Pooley Karen, Pierce Angela, Hopkisson James F
University of Nottingham, Nottingham University Hospital, United Kingdom.
Hum Fertil (Camb). 2010 Sep;13(3):159-67. doi: 10.3109/14647273.2010.512654.
The marked decline in the number of sperm donors recruited in the UK has been largely attributed to changes in regulations and in particular those related to the removal of anonymity. After a 5-year period of inactivity, the sperm donor bank in Nottingham was provided with limited resources to try and recruit donors who were willing to be identified on the HFEA register. Marketing was sporadic and at first low cost and the enquiry rate only increased significantly when the centre's website became operational and higher cost advertising was used. Over a 4-year period, a total of 151 enquiries gave rise to 14 useable donors at a cost of approximately £5,500 each. Donor sperm was generally of high quality having been density gradient prepared prior to cryopreservation and provided an overall ongoing pregnancy rate of 21.6% and 45.6% by IUI and IVF, respectively. The overall exercise demonstrated that identifiable donors were coming forward but in lower numbers compared to those observed before 2005. At current treatment prices, centres should be aware that recouping the costs of donor recruitment and processing may be difficult and that the cost of both donor sperm and donor insemination are likely to rise significantly.
英国招募精子捐赠者的数量显著下降,这在很大程度上归因于法规的变化,尤其是与取消匿名性相关的法规变化。经过5年的停滞期后,诺丁汉的精子库获得了有限的资源,试图招募愿意在人类受精与胚胎学管理局(HFEA)登记册上被识别的捐赠者。营销活动是零星的,起初成本较低,只有当该中心的网站开始运营并采用成本更高的广告时,咨询率才显著提高。在4年的时间里,总共151次咨询产生了14名可用的捐赠者,每名捐赠者的成本约为5500英镑。捐赠的精子质量普遍较高,在冷冻保存前经过密度梯度处理,通过宫内人工授精(IUI)和体外受精(IVF)的总体持续妊娠率分别为21.6%和45.6%。总体情况表明,可识别的捐赠者正在出现,但与2005年之前观察到的数量相比有所减少。按照目前的治疗价格,各中心应意识到,收回捐赠者招募和处理的成本可能很困难,而且捐赠精子和捐赠人工授精的成本可能会大幅上升。