Larsen Inge Kristine, Gradel Kim O, Helms Morten, Hornstrup Maren Kathrine, Jürgens Gesche, Mens Helene, Rosager Christine Linaa, Clausen Thomas Holtkøtter, Kronborg Gitte, Nielsen Henrik
Department of Infectious Diseases, Aalborg Hospital, Aarhus University Hospitals, Aalborg, Denmark.
Scand J Infect Dis. 2011 Jan;43(1):3-7. doi: 10.3109/00365548.2010.517780. Epub 2010 Sep 20.
Non-typhoidal Salmonella (NTS) and Campylobacter are common causes of diarrhoea in human immunodeficiency virus (HIV)-positive patients. To investigate if incidence has changed since the introduction of highly active antiretroviral therapy (HAART), we combined data from The Danish Surveillance Registry for Enteric Pathogens and The Danish National Hospital Registry. We found that the incidences of NTS- and Campylobacter-related illness among HIV-positive patients in Denmark have declined since the introduction of HAART, although the incidences remained higher compared to the background population. Moreover our study suggests that there is an increased incidence of Campylobacter-related illness among homosexual men in the HIV-positive population.
非伤寒沙门氏菌（NTS）和弯曲杆菌是人类免疫缺陷病毒（HIV）阳性患者腹泻的常见病因。为了调查自高效抗逆转录病毒疗法（HAART）引入以来发病率是否发生了变化，我们合并了丹麦肠道病原体监测登记处和丹麦国家医院登记处的数据。我们发现，自HAART引入以来，丹麦HIV阳性患者中与NTS和弯曲杆菌相关疾病的发病率有所下降，尽管与背景人群相比发病率仍然较高。此外，我们的研究表明，HIV阳性人群中同性恋男性弯曲杆菌相关疾病的发病率有所增加。
