衰老对病毒感染的影响。
Impact of aging on viral infections.
机构信息
Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA.
出版信息
Microbes Infect. 2010 Dec;12(14-15):1120-4. doi: 10.1016/j.micinf.2010.08.009. Epub 2010 Sep 16.
Abstract
Older people are more susceptible to a variety of viral infections, including those that induce respiratory disease, resulting in higher morbidity and mortality than younger people. Aging impacts both innate and adaptive arms of the immune system to impair control of viral infections. This review will summarize key findings on how aging impacts immunity to viral infection.
摘要
老年人更容易受到各种病毒感染的影响，包括引起呼吸道疾病的感染，导致发病率和死亡率高于年轻人。衰老影响先天和适应性免疫系统，损害对病毒感染的控制。本文将总结关于衰老如何影响对病毒感染的免疫的关键发现。
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