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[N,N-亚烷基-双-(取代苯酚)甘氨酸的合成用于大鼠体内放射性锕系元素的去除]

[Synthesis of N,N-alkylene-bis-(substituted-phenol)glycine for removal of radio-actinides in rats].

作者信息

Sun M Z, Zhu P E, Tang C, Chen A F, Shen B Y

机构信息

Shanghia Medical University, Institute of Radiation Medicine.

出版信息

Yao Xue Xue Bao. 1990;25(7):505-8.

PMID:2085126
Abstract

The synthesis of 16 compounds of N, N-alkylene-bis (substituted phenol) glycine is reported. They showed good effects on the removal of redinuclide thorium-234 from rats, except compound 3 and compound 4. Two of them can remove more than 70% of injected thorium. The relationship between structure and effects of these compounds was discussed.

摘要

报道了16种N，N-亚烷基-双（取代苯酚）甘氨酸化合物的合成。除化合物3和化合物4外，它们对大鼠体内放射性核素钍-234的去除显示出良好效果。其中两种化合物能去除超过70%的注入钍。讨论了这些化合物的结构与效果之间的关系。

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