Department of Geriatric Medicine, Unit 4, Merlin Park University Hospital, Galway, Ireland.
J Neurol Neurosurg Psychiatry. 2011 May;82(5):500-4. doi: 10.1136/jnnp.2010.214817. Epub 2010 Sep 18.
Testing of orientation to time is an important part of mental status examination. The validity of errors in different aspects of temporal orientation was examined in older hospital patients as a guide to the presence of dementia or delirium and as a measure of the severity of dementia, as defined by the Global Deterioration Scale.
Inpatients and outpatients attending an acute hospital underwent independent assessments by two doctors on the same day to determine orientation to time and cognitive status. Optimum cut-offs for error scores on the different aspects of temporal orientation were calculated to maximise the sum of sensitivity and specificity for detection of dementia or delirium.
Of the 262 patients assessed, 62 (23.7%) had dementia or delirium. The best cut-offs for detection of these disorders were: any error in identifying the year, month, day of the month or day of the week; and an error of more than 1 h in identifying the time of day. Failure to identify the year correctly was the most valuable single sign of dementia or delirium (sensitivity 86% and specificity 94%); failure to identify either year or month correctly was 95% sensitive and 86.5% specific for the detection of cognitive impairment. Severity of temporal disorientation, measured using a number of approaches, was strongly associated with severity of dementia.
Disorientation to time is a useful guide to the presence and severity of dementia or delirium in older hospital patients. Failure to identify the year or month correctly is a sufficiently sensitive and specific indicator of dementia or delirium to warrant more detailed cognitive assessment in this population.
时间定向测试是精神状态检查的重要组成部分。本研究旨在探讨老年住院患者时间定向错误的各维度在痴呆或谵妄诊断中的有效性,并评估其作为全球衰退量表(Global Deterioration Scale)定义的痴呆严重程度的指标。
本研究对同日接受两位医生评估的住院和门诊患者进行时间定向和认知状态的独立评估。计算不同时间定向维度错误评分的最佳截断值,以最大化检测痴呆或谵妄的灵敏度和特异性之和。
在 262 例评估患者中,62 例(23.7%)存在痴呆或谵妄。这些疾病的最佳检测截断值为:识别年份、月份、日和星期的任何错误;以及识别时间的错误超过 1 小时。不能正确识别年份是痴呆或谵妄的最有价值的单一表现(灵敏度 86%,特异性 94%);不能正确识别年份或月份可 95%敏感和 86.5%特异性地检测认知障碍。使用多种方法测量的时间定向障碍严重程度与痴呆严重程度密切相关。
时间定向障碍是老年住院患者痴呆或谵妄存在和严重程度的有用指标。不能正确识别年份或月份是痴呆或谵妄的一个足够敏感和特异的指标,因此在该人群中需要进行更详细的认知评估。