Department of Clinical Sciences, Danderyd Hospital, Karolinska Institutet, 18288 Stockholm, Sweden.
Department of Rehabilitation Medicine, Danderyd University Hospital, 18288 Stockholm, Sweden.
Int J Environ Res Public Health. 2022 Mar 25;19(7):3928. doi: 10.3390/ijerph19073928.
This study investigated associations between time processing ability (TPA), daily time management (DTM), and dementia severity. Persons with dementia (PwDs) ( = 53) and their significant others ( = 49) participated in this cross-sectional study. Bivariate analyses were used to investigate associations between TPA and DTM and the dementia severity. Linear regression models were used to further predict the contribution of the subtests in the Mini Mental State Examination (MMSE) for TPA results. The results showed significant correlations between TPA and dementia severity, where visuospatial functions were the most highly correlated. TPA also showed a significant correlation to proxy-rated DTM. In addition, proxy-rated DTM was significantly correlated with dementia severity and PwDs' own self-ratings of their DTM. Knowledge of the association between TPA, dementia severity, and visuospatial functions can enable early detection of TPA impairments. For a comprehensive assessment of TPA and DTM, objective measures should be used in combination with self-ratings and proxy-ratings. The findings can be used in clinical research and healthcare settings to develop methods to compensate for impaired TPA and support DTM in PwDs.
本研究调查了时间处理能力(TPA)、日常时间管理(DTM)与痴呆严重程度之间的关系。痴呆患者(PwD)(n=53)及其主要照顾者(n=49)参与了这项横断面研究。采用双变量分析来调查 TPA 和 DTM 与痴呆严重程度之间的关联。采用线性回归模型进一步预测了 Mini 精神状态检查(MMSE)中各项测试对 TPA 结果的贡献。结果显示 TPA 与痴呆严重程度之间存在显著相关性,其中视空间功能相关性最高。TPA 与代理评定的 DTM 也呈显著相关。此外,代理评定的 DTM 与痴呆严重程度以及 PwD 自身对 DTM 的自评呈显著相关。了解 TPA、痴呆严重程度和视空间功能之间的关联可以帮助早期发现 TPA 损伤。为了全面评估 TPA 和 DTM,应结合自我评估和代理评估使用客观测量。研究结果可用于临床研究和医疗保健环境,以开发方法来补偿受损的 TPA 并支持 PwD 的 DTM。