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[腮腺中度恶性肿瘤]

[Medium-malignancy tumors of the parotid gland].

作者信息

Piquet J J, Roux X, Chevalier D, Thill C, Parent M, Lecomte Houcke M

机构信息

Service ORL, CHU Lille.

出版信息

Ann Otolaryngol Chir Cervicofac. 1990;107(8):532-7.

PMID:2085255
Abstract

Among the 437 parotidectomies performed from 1966 to 1989, we observed 2 acinar-cell tumors and 11 mucoepidermoid carcinomas, ie. 3%. The acinar-cell tumors occurred in 2 men aged 45 and 71. A conservative complete parotidectomy was performed in both cases with a 6 and 7-year survival without local recurrence. The mucoepidermoid tumors affected 4 women and 7 men. The clinical appearance in 2 cases was highly suggestive of a malignant tumor, the picture including facial palsy, fixed gaze and adenopathy. In spite of excision completed by radiation therapy, the outcome soon was unfavorable. In the other 9 patients presenting with a limited tumor of the parotid gland, the facial nerve had to be partly sacrificed in 2 cases because no dissection was possible even under a microscope. The prognosis was generally favorable in the limited forms with 6/6 patients alive at more than 5 years and 3 patients alive at 3 years, 2 years and 1 year. Postoperative radiation therapy was not performed systematically, but only in 2/3 of cases (ill-delineated or ill-differentiated tumor).

摘要

在1966年至1989年期间实施的437例腮腺切除术患者中,我们观察到2例腺泡细胞肿瘤和11例黏液表皮样癌,即占3%。腺泡细胞肿瘤发生在2名年龄分别为45岁和71岁的男性身上。两例均实施了保守性腮腺全切除术,患者分别存活6年和7年,无局部复发。黏液表皮样肿瘤患者中,女性4例,男性7例。2例患者的临床表现高度提示为恶性肿瘤,症状包括面瘫、凝视固定和腺病。尽管手术切除后进行了放射治疗,但预后很快就不理想。在其他9例腮腺局限性肿瘤患者中,2例因即使在显微镜下也无法进行解剖而不得不部分牺牲面神经。局限性肿瘤患者的预后总体良好,6例患者中6例存活超过5年,3例患者分别存活3年、2年和1年。术后放射治疗并非系统进行,仅在2/3的病例(肿瘤边界不清或分化不良)中实施。

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