Belloc J B, Laccourreye O, Chabardes E, Carnot F, Brasnu D, Laccourreye H
Service d'Oto-Rhino-Laryngologie et de Chirurgie Cervico-Faciale, Hôpital Laënnec, Paris.
Ann Otolaryngol Chir Cervicofac. 1991;108(2):119-25.
On the basis of a retrospective series of thirteen cases treated between 1969 and 1989, the authors have studied the diagnostic and therapeutic issues connected with mucoepidermoid parotid tumors. The diagnosis is histopathological, but it is sometimes difficult to establish because of the histological polymorphism of these tumors. The degree of malignancy is variable and generally low. It is determined according to clinical and histopathological criteria, although there is not always a correlation between these criteria and the malignancy of evolution. Surgical exeresis is sufficient to cure most of these tumors. However, postoperative radiation therapy is indicated in case of tumoral invasion. Out of the ten cases of mucoepidermoid parotid tumor, nine were treated in first intention with exclusive surgery, and one case underwent postoperative radiation therapy. No local recurrence was noted. Out of the three patients who had a second-intention surgical exeresis, one died after repeated recurrence in spite of the complementary radiation therapy.
基于1969年至1989年间治疗的13例回顾性病例系列,作者研究了与腮腺黏液表皮样癌相关的诊断和治疗问题。诊断依靠组织病理学,但由于这些肿瘤的组织学多态性,有时难以确诊。恶性程度各不相同,总体较低。根据临床和组织病理学标准确定恶性程度,尽管这些标准与肿瘤进展的恶性程度之间并不总是存在相关性。手术切除足以治愈大多数此类肿瘤。然而,肿瘤侵犯时需进行术后放疗。在10例腮腺黏液表皮样癌病例中,9例首先采用单纯手术治疗,1例接受了术后放疗。未观察到局部复发。在3例二期手术切除的患者中,1例尽管接受了辅助放疗,但在反复复发后死亡。