Douglas H E
Canniesburn Plastic Surgery Unit, Glasgow, UK.
J Wound Care. 2010 Sep;19(9):403-6. doi: 10.12968/jowc.2010.19.9.78235.
TGF-ß, a growth factor involved in various stages of the wound healing process, exists in three different isoforms. Experimental models have shown these isoforms to be functionally different and one of them, TGF-ß3, has the potential to reduce scarring in clinical practice. This literature review explores the role of TGF- in wound healing, examining the research to date.
转化生长因子β(TGF-β)是一种参与伤口愈合过程各个阶段的生长因子,以三种不同的异构体形式存在。实验模型表明,这些异构体在功能上有所不同,其中一种,即TGF-β3,在临床实践中具有减少瘢痕形成的潜力。这篇文献综述探讨了TGF-β在伤口愈合中的作用,并审视了迄今为止的相关研究。