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多孔整体材料:生物分析中小体积提取的吸附剂。

Porous monoliths: sorbents for miniaturized extraction in biological analysis.

机构信息

Tongji School of Pharmacy, Huazhong University of Science and Technology, Wuhan 430030, China.

出版信息

Anal Bioanal Chem. 2011 Apr;399(10):3345-57. doi: 10.1007/s00216-010-4190-x. Epub 2010 Sep 19.

DOI:10.1007/s00216-010-4190-x
PMID:20852850
Abstract

In this review the focus is on application of porous monoliths to miniaturized extraction of biological analysis, with emphasis on porous monolithic materials and different miniaturized extraction formats. The general approaches used to synthesize organic polymer and silica monolithic materials are highlighted, and their properties and applicability are described and compared. Several extraction formats, including in-tube microextraction, chip-based microextraction, tip-based microextraction, among others, are reviewed in depth.

摘要

在本次综述中,重点介绍了多孔整体材料在生物分析微萃取中的应用,尤其强调了多孔整体材料和不同的微萃取形式。本文突出了用于合成有机聚合物和硅胶整体材料的一般方法,并对其性能和适用性进行了描述和比较。详细回顾了几种萃取形式,包括管内微萃取、芯片基微萃取、尖端基微萃取等。

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