了解肿瘤干细胞在多形性胶质母细胞瘤中的作用：一篇综述文章。
Understanding the role of tumor stem cells in glioblastoma multiforme: a review article.
机构信息
Neurosurgical Laboratory for Translational Stem Cell Research, Department of Neurosurgery, Weill Cornell Brain Tumor Center, Weill Cornell Medical College of Cornell University, 510 E 70th Street, New York, NY 10021, USA.
出版信息
J Neurooncol. 2011 Jul;103(3):397-408. doi: 10.1007/s11060-010-0406-3. Epub 2010 Sep 18.
PMID:20853017
Abstract
It has been hypothesized that cancer stem cells (CSC) may account for the pathogenesis underlying various tumors, including GBM. Markers of these CSCs can be potentially used as therapeutic targets. In this review, we discuss the most recent information regarding CSCs, their molecular biology and their potential role in GBM.
摘要
人们推测，癌症干细胞（CSC）可能是包括 GBM 在内的各种肿瘤发生的基础。这些 CSC 的标志物可能被用作治疗靶点。在这篇综述中，我们讨论了有关 CSC 的最新信息，包括它们的分子生物学及其在 GBM 中的潜在作用。
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