用于白内障手术局部麻醉的含或不含2%利多卡因凝胶的0.5%丁卡因滴眼液
Tetracaine 0.5% eyedrops with or without lidocaine 2% gel in topical anesthesia for cataract surgery.
作者信息
Tsoumani Anthoula T, Asproudis Ioannis C, Damigos Dimitrios
机构信息
Department of Ophthalmology University Hospital of Ioannina, Greece.
出版信息
Clin Ophthalmol. 2010 Sep 7;4:967-70. doi: 10.2147/opth.s11755.
BACKGROUND AND OBJECTIVE
To evaluate the level of pain during phacoemulsification and foldable intraocular lens implantation under instillation of tetracaine 0.5% eyedrops versus a combination of lidocaine 2% gel and instillation of tetracaine eyedrops.
METHODS
This prospective, randomized, controlled study included 51 patients undergoing phacoemulsification under topical anesthesia. They were randomized into two groups based on the topical anesthetic method they were to receive. Preoperatively all patients were asked to answer a questionnaire. One hour postoperatively, they were asked to grade their intraoperative and postoperative pain on a visual analog scale from 0 to 10.
RESULTS
There were no statistically significant differences between the two methods of anesthesia. Gender and the presence of relatives or friends were independent factors playing a significant role in pain sensitivity.
CONCLUSIONS
The combination of lidocaine 2% gel and tetracaine eyedrops does not have a better analgesic result than a single instillation of tetracaine 0.5% eyedrops.
背景与目的
评估在滴注0.5%丁卡因滴眼液与2%利多卡因凝胶联合滴注丁卡因滴眼液的情况下，白内障超声乳化吸除术及折叠式人工晶状体植入术中的疼痛程度。
方法
这项前瞻性、随机、对照研究纳入了51例接受表面麻醉下白内障超声乳化吸除术的患者。根据他们将接受的表面麻醉方法将其随机分为两组。术前所有患者均被要求回答一份问卷。术后1小时，要求他们使用0至10的视觉模拟量表对术中及术后疼痛进行评分。
结果
两种麻醉方法之间无统计学显著差异。性别以及亲属或朋友的陪伴是在疼痛敏感性方面起重要作用的独立因素。
结论
2%利多卡因凝胶与丁卡因滴眼液联合使用的镇痛效果并不优于单次滴注0.5%丁卡因滴眼液。
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