老年人参与早期癌症临床试验的障碍。
Barriers to enrollment of elderly adults in early-phase cancer clinical trials.
机构信息
University of Colorado Cancer Center and Colorado Health Outcomes Program, Aurora, CO; Moffitt Cancer Center, Tampa, FL.
出版信息
J Oncol Pract. 2008 Jul;4(4):162-8. doi: 10.1200/JOP.0842001.
Abstract
Potential strategies to overcome barriers to enrollment of seniors into early-phase trials.
摘要
克服老年人参与早期临床试验障碍的潜在策略。
相似文献
1
Barriers to enrollment of elderly adults in early-phase cancer clinical trials.老年人参与早期癌症临床试验的障碍。
J Oncol Pract. 2008 Jul;4(4):162-8. doi: 10.1200/JOP.0842001.
2
Phase 1 Clinical Trials in the Elderly: Enrollment Challenges.老年人的1期临床试验：入组挑战。
J Adv Pract Oncol. 2020 Jul;11(5):494-501. doi: 10.6004/jadpro.2020.11.5.5. Epub 2020 Jul 1.
3
Overcoming Barriers: Evidence-Based Strategies to Increase Enrollment of Underrepresented Populations in Cancer Therapeutic Clinical Trials-a Narrative Review.克服障碍：增加癌症治疗临床试验中代表性不足人群入组的循证策略——叙述性综述。
J Cancer Educ. 2020 Oct;35(5):841-849. doi: 10.1007/s13187-019-01650-y.
4
Participation of the elderly population in clinical trials: barriers and solutions.老年人群参与临床试验：障碍与解决方案。
Cancer Control. 2014 Jul;21(3):209-14. doi: 10.1177/107327481402100305.
5
Overcoming Barriers to Clinical Trial Enrollment.克服临床试验入组障碍。
Am Soc Clin Oncol Educ Book. 2019 Jan;39:105-114. doi: 10.1200/EDBK_243729. Epub 2019 May 17.
6
Barriers to Clinical Trial Enrollment in Patients With Pancreatic Adenocarcinoma Eligible for Early-Phase Clinical Trials.适合参加早期临床试验的胰腺导管腺癌患者参与临床试验的障碍。
Oncology (Williston Park). 2020 Oct 9;34(10):407-412. doi: 10.46883/ONC.2020.3410.0407.
7
Research Staff Perspectives on Cancer Clinical Trials and Barriers to Recruitment: A Qualitative Research.研究人员对癌症临床试验及招募障碍的看法：一项定性研究
Cureus. 2021 Aug 15;13(8):e17202. doi: 10.7759/cureus.17202. eCollection 2021 Aug.
8
Barriers and facilitators of clinical trial enrollment in a network of community-based pediatric oncology clinics.社区儿科肿瘤诊所网络中临床试验入组的障碍和促进因素。
Pediatr Blood Cancer. 2020 Apr;67(4):e28023. doi: 10.1002/pbc.28023. Epub 2019 Sep 25.
9
Analysis of Factors Affecting Successful Clinical Trial Enrollment in the Context of Three Prospective, Randomized, Controlled Trials.在三项前瞻性、随机、对照试验背景下影响临床试验成功入组因素的分析
Int J Radiat Oncol Biol Phys. 2017 Mar 15;97(4):770-777. doi: 10.1016/j.ijrobp.2016.11.035. Epub 2016 Nov 27.
10
Enrollment Trends and Disparity Among Patients With Lung Cancer in National Clinical Trials, 1990 to 2012.1990年至2012年全国肺癌临床试验患者的入组趋势及差异
J Clin Oncol. 2016 Nov 20;34(33):3992-3999. doi: 10.1200/JCO.2016.67.7088. Epub 2016 Sep 30.
引用本文的文献
1
Comparison of baseline patient characteristics in phase 1 and phase 2/3 clinical trials for anticancer treatments.抗癌治疗1期和2/3期临床试验中患者基线特征的比较。
J Transl Med. 2025 May 16;23(1):547. doi: 10.1186/s12967-025-06509-z.
2
Factors influencing clinical trial participation of women with fibromyalgia across the United States: a cross-sectional survey.影响美国纤维肌痛女性参与临床试验的因素：一项横断面调查。
Women Health. 2024 May-Jun;64(5):369-379. doi: 10.1080/03630242.2024.2334700. Epub 2024 May 14.
3
COVID-19 clinical trial participation and awareness in Texas.德克萨斯州的新冠病毒疾病（COVID-19）临床试验参与情况与认知度
Hum Vaccin Immunother. 2024 Dec 31;20(1):2340692. doi: 10.1080/21645515.2024.2340692. Epub 2024 Apr 24.
4
Exploring the barriers to, and importance of, participant diversity in early-phase clinical trials: an interview-based qualitative study of professionals and patient and public representatives.探索早期临床试验中参与者多样性的障碍和重要性：基于访谈的专业人员、患者和公众代表的定性研究。
BMJ Open. 2024 Mar 19;14(3):e075547. doi: 10.1136/bmjopen-2023-075547.
5
Community Engagement Strategies for Underrepresented Racial and Ethnic Populations.针对代表性不足的种族和族裔群体的社区参与策略
Mayo Clin Proc. 2024 Jan;99(1):159-171. doi: 10.1016/j.mayocp.2023.07.015.
6
Access to early-phase clinical trials in older patients with cancer in France: the EGALICAN-2 study.在法国，癌症老年患者参与早期临床试验的途径：EGALICAN-2 研究。
ESMO Open. 2022 Jun;7(3):100468. doi: 10.1016/j.esmoop.2022.100468. Epub 2022 May 6.
7
Ecological Predictors of Older Adults' Participation and Retention in a Physical Activity Intervention.老年人参与和坚持体育活动干预的生态预测因素。
Int J Environ Res Public Health. 2022 Mar 8;19(6):3190. doi: 10.3390/ijerph19063190.
8
Older adult participation in cancer clinical trials: A systematic review of barriers and interventions.老年人参与癌症临床试验：障碍和干预措施的系统评价。
CA Cancer J Clin. 2021 Jan;71(1):78-92. doi: 10.3322/caac.21638. Epub 2020 Oct 1.
9
Barriers to clinical trial enrollment of older adults with cancer: A qualitative study of the perceptions of community and academic oncologists.老年癌症患者临床试验入组的障碍：一项关于社区和学术肿瘤学家看法的定性研究
J Geriatr Oncol. 2020 Mar;11(2):327-334. doi: 10.1016/j.jgo.2019.07.017. Epub 2019 Jul 31.
10
Health-Related Quality of Life in Older Adults with Colorectal Cancer.老年人结直肠癌患者的健康相关生活质量。
Curr Oncol Rep. 2019 Jul 29;21(9):81. doi: 10.1007/s11912-019-0830-2.
本文引用的文献
1
Understanding the attitudes of the elderly towards enrolment into cancer clinical trials.了解老年人对参与癌症临床试验的态度。
BMC Cancer. 2006 Feb 8;6:34. doi: 10.1186/1471-2407-6-34.
2
Systematic review of barriers to the recruitment of older patients with cancer onto clinical trials.关于招募老年癌症患者参与临床试验的障碍的系统评价
J Clin Oncol. 2005 May 1;23(13):3112-24. doi: 10.1200/JCO.2005.00.141.
3
Enrollment of elderly patients in clinical trials for cancer drug registration: a 7-year experience by the US Food and Drug Administration.老年患者参与癌症药物注册临床试验情况：美国食品药品监督管理局七年经验
J Clin Oncol. 2004 Nov 15;22(22):4626-31. doi: 10.1200/JCO.2004.02.175.
4
Cancer statistics, 2004.2004年癌症统计数据。
CA Cancer J Clin. 2004 Jan-Feb;54(1):8-29. doi: 10.3322/canjclin.54.1.8.
5
Barriers to clinical trial participation by older women with breast cancer.老年乳腺癌女性参与临床试验的障碍。
J Clin Oncol. 2003 Jun 15;21(12):2268-75. doi: 10.1200/JCO.2003.09.124.
6
Enrollment of older patients in cancer treatment trials in Canada: why is age a barrier?加拿大老年患者参与癌症治疗试验的情况：为何年龄成为了障碍？
J Clin Oncol. 2003 Apr 15;21(8):1618-23. doi: 10.1200/JCO.2003.12.044.
7
Participation of patients 65 years of age or older in cancer clinical trials.65岁及以上患者参与癌症临床试验的情况。
J Clin Oncol. 2003 Apr 1;21(7):1383-9. doi: 10.1200/JCO.2003.08.010.
8
Prospective evaluation of cancer clinical trial accrual patterns: identifying potential barriers to enrollment.癌症临床试验入组模式的前瞻性评估：识别入组的潜在障碍。
J Clin Oncol. 2001 Mar 15;19(6):1728-33. doi: 10.1200/JCO.2001.19.6.1728.
9
Clinical research in the older cancer patient.老年癌症患者的临床研究。
Hematol Oncol Clin North Am. 2000 Feb;14(1):283-91. doi: 10.1016/s0889-8588(05)70289-6.
10
Aging and cancer in America. Demographic and epidemiologic perspectives.美国的衰老与癌症。人口统计学和流行病学视角。
Hematol Oncol Clin North Am. 2000 Feb;14(1):17-23. doi: 10.1016/s0889-8588(05)70275-6.
Zotero 插件