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健康受试者外周血淋巴细胞亚群中的线粒体间连接。

Intermitochondrial junctions in a subpopulation of peripheral blood lymphocytes from healthy subjects.

作者信息

Richard S, Masse J M, Guichard J, Breton-Gorius J

机构信息

Laboratoire de Neurohistologie EPHE, Hôpital de la Salpêtrière, Paris, France.

出版信息

Biol Cell. 1990;70(1-2):27-32. doi: 10.1016/0248-4900(90)90357-9.

Abstract

This paper reports the observation of intermitochondrial junctions (IMJ) with a periodicity of 15.4 +/- 0.65 nm in peripheral blood lymphocytes of healthy subjects. The percentage of IMJ-containing cells appears constant (about 10% of examined lymphocytes) and is independent of the delay of fixation. Immunogold staining reveals that lymphocytes with IMJ exhibit a T-phenotype. IMJ have been reported in other types of tissues but, to our knowledge, have not been previously described in the blood cell. The signification of these structures is discussed.

摘要

本文报道了在健康受试者外周血淋巴细胞中观察到线粒体间连接(IMJ),其周期为15.4±0.65纳米。含有IMJ的细胞百分比似乎恒定(约占所检查淋巴细胞的10%),且与固定延迟无关。免疫金染色显示,具有IMJ的淋巴细胞表现出T表型。IMJ已在其他类型的组织中被报道,但据我们所知,此前尚未在血细胞中被描述。本文讨论了这些结构的意义。

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