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自组装三明治免疫测定中纳米级石墨烯对量子点的无距离猝灭。

Distance-independent quenching of quantum dots by nanoscale-graphene in self-assembled sandwich immunoassay.

机构信息

Key Laboratory of Industrial Ecology and Environmental Engineering (Ministry of Education, China), School of Environmental and Biological Science and Technology, Dalian University of Technology, Dalian 116024, China.

出版信息

Chem Commun (Camb). 2010 Nov 14;46(42):7909-11. doi: 10.1039/c0cc02085k. Epub 2010 Sep 21.

DOI:10.1039/c0cc02085k
PMID:20856985
Abstract

A promising one-step homogeneous fluoroimmunoassay based on nanoscale-graphene sheets as powerful fluorescence acceptors and CdTe quantum dots as vigorous donors was designed to detect trace biomarker protein with distance-independent quenching efficiency, which significantly broke the distance limit (100 Å) in traditional fluorescent biosensors.

摘要

一种基于纳米级石墨烯片作为强大的荧光受体和 CdTe 量子点作为有力供体的有前途的一步均相荧光免疫分析方法被设计用于检测痕量生物标志物蛋白,具有距离无关的猝灭效率,这显著打破了传统荧光生物传感器的距离限制(100 Å)。

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