Department of Cranio-Maxillo-Facial Surgery, University of Regensburg, Regensburg, Germany.
Clin Oral Investig. 2011 Apr;15(2):127-39. doi: 10.1007/s00784-010-0450-6. Epub 2010 Sep 22.
Chronic graft-versus-host disease (cGVHD) is a multi-organ disease that occurs post-hematopoietic stem cell transplantation, with the mouth being one of the most frequently affected organs. In 2009, the German-Austrian-Swiss working party on bone marrow and blood stem cell transplantation held a consensus conference to define clinical management of cGVHD. The consensus conference aimed to summarize the literature on diagnosis and topical treatment options for oral cGVHD and to provide recommendations for clinical practice, including routine dental and oral care as well as monitoring for secondary malignancies and bisphophonate-induced osteonecrosis of the jaw.
慢性移植物抗宿主病(cGVHD)是一种发生于造血干细胞移植后的多器官疾病,口腔是最常受累的器官之一。2009 年,德国-奥地利-瑞士骨髓和造血干细胞移植工作组召开了一次共识会议,以定义 cGVHD 的临床管理。该共识会议旨在总结口腔 cGVHD 的诊断和局部治疗选择的文献,并为临床实践提供建议,包括常规口腔护理和监测口腔继发性恶性肿瘤和双膦酸盐相关的颌骨坏死。