高效钯催化的杂环官能化胺化反应。
Efficient Pd-catalyzed amination reactions for heterocycle functionalization.
机构信息
Department of Chemistry, Room 18-490, Massachusetts Institute of Technology, Cambridge Massachusetts 02139, USA.
出版信息
Org Lett. 2010 Oct 15;12(20):4442-5. doi: 10.1021/ol101929v.
Abstract
The Pd-catalyzed amination of unprotected benzo-fused heterocycles is reported, which allows for greater flexibility and efficiency in the modification of this important class of molecules. The generality of these simple and efficient procedures is demonstrated through the synthesis of a wide variety of structural types.
摘要
报道了 Pd 催化的未保护苯并稠合杂环的胺化反应，这为这类重要分子的修饰提供了更大的灵活性和效率。这些简单高效的方法的通用性通过合成各种结构类型的化合物得到了证明。
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